IgM plasma cell myeloma (PCM) is a rare entity, and CD19 positivity is found in only 1-4% of PCM. Here we report a unique case of IgM PCM, in which the plasma cells are positive for CD19. Clinically, the patient presented with hyperviscosity syndrome, mimicking the clinical manifestation of Waldenstrom's macroglobulinemia. In addition, the IgM para-protein from the patient behaved like cryoglob...

We present the theory and implementation for computing the (free) energy and its analytical gradients with the Brueckner doubles (BD) coupled cluster method in solution, in combination with the polarizable continuum model of solvation (PCM). The complete model, called PTED, and an efficient approximation, called PTE, are introduced and tested with numerical examples. Implementation details are ...

Separating digestive and urinary outlets is a critical step during mammalian embryogenesis. However, the natural history of these structures is poorly studied, and little is known about their embryonic origin. Here, we show that peri-cloacal mesenchymal (PCM) progenitors are the major source of these structures. Surprisingly, PCM progenitors also contribute to perineum, a structural barrier sep...

Phase change memory (PCM) is one of the frontrunners among the emerging non-volatile memory technologies. Even though a Joule-heating-induced phase change mechanism has been demonstrated down to a few nanometer dimensions, a key factor that could possibly limit the scaling trends in a PCM memory array is the thermal cross-talk between adjacent cells. In this article we present a compact electro...

Many cells express a membrane-coupled external mechanical layer, the pericellular matrix (PCM), which often contains long-chain polymers. Its role and properties are not entirely known, but its functions are believed to include physical protection, mechanosensing, chemical signalling or lubrication. The viscoelastic response of the PCM, with polysaccharides as the main structural components, is...

There are several emerging memory technologies looming on the horizon to compensate the physical scaling challenges of DRAM. Phase change memory (PCM) is one of such candidates proposed for being part of the main memory in computing systems. One salient feature of PCM is its multi-level cell (MLC) property which can be used to multiply the memory capacity at the cell level. However, due to the ...

The solvated supermolecular approach, i.e., block-localized wave function coupled with polarizable continuum model (BLW/PCM), was proposed to calculate molecular ionization potential (IP), electron affinity (EA) in the solid phase, and related electronic polarization. Via the calculations of a solvated supermolecule (5M), including four closest molecules, BLW/PCM overcomes the limitation in the...

passive solar systems such as solar chimneys need solar radiation in order to work. therefore, they cannot present stable natural ventilation when solar energy vanishes: to have a more robust and stable condition, solar energy should be stored during the day and released back during the night. phase change materials can save additional thermal energy during the day and release it during the nig...

the study addresses performance control matrix (pcm) to determine service quality items of priority for improvement. most businesses focus on customer satisfaction when undertaking surveys of satisfaction and dissatisfaction, while generally neglecting employee satisfaction. therefore, this study develops an integrated model to improve service quality in taiwanese finance industry employees. a ...

We study the integrable bi-Yang-Baxter deformation of $SU(2)$ principal chiral model (PCM) and its finite action uniton solutions. Under an adiabatic compactification on $S^1$, we obtain a quantum mechanics with elliptic Lam\'e-like potential. perform perturbative calculation ground state energy in this to large orders obtaining asymptotic series. Using Borel-Pad\'e technique, determine expecte...