نتایج جستجو برای: 2 inhibitory

تعداد نتایج: 2614873  

Nitro-containing heteroaromatic derivatives structurally related to nitroimidazole (Metronidazole) are being extensively evaluated against Helicobacter pylori isolates. On the other hand, 1,3,4-thiadiazole derivatives have also demonstrated promising antibacterial potential. In present study, we evaluated anti-H. pylori activity of novel hybrid molecules bearing nitroaryl and 1,3,4-thiadiazole ...

Journal: :مجله دانشگاه علوم پزشکی کرمانشاه 0
mohammad kazem gharib naseri assistant professor of physiology ahwaz university of medical sciences, ahvaz, iran (corresponding author)

background& objectives: zataria multiflora boiss is used in traditional medicine to treat gastrointestinal disorders and menorrhagia. the inhibitory effect of this herb on rat uterus contractions has also been reported. the aim of this study was to investigate the effect of zataria multiflora boiss hydroalcoholic leaf extract (zhle) on isolated rat ileum in presence of some known ileum stimulan...

Journal: :iranian journal of basic medical sciences 0
nona pooryaghoobi 1department of chemistry, mashhad branch, islamic azad university, mashhad, ir iran mehdi bakavoli department of chemistry, school of sciences, ferdowsi university of mashhad, mashhad, 917751436, ir iran maliheh alimardani student research committee, department of laboratory sciences, school of paramedical sciences, mashhad university of medical sciences, mashhad, ir iran tahmineh bazzazan 2department of chemistry, school of sciences, ferdowsi university of mashhad, mashhad, 917751436, ir iran hamid sadeghian antimicrobial resistance research center, mashhad university of medical sciences, mashhad 91967-73117, ir iran 5 department of laboratory sciences, school of paramedical sciences, mashhad university of medical sciences, mashhad, ir iran

objective(s): recently we reported that the soybean 15-lipoxygenase (slo) inhibitory activity of pyrimido[4,5-b][l,4]benzothiazines largely depends on the orientation of sulfur atom of thiazine core towards feiii-oh in the active site pocket of the enzyme with subsequent oxidation of sulfur to sulfoxide. in this paper the results of a comparative study on the slo inhibitory activities of the me...

Journal: :International Journal of Current Microbiology and Applied Sciences 2018

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