Many amyloid inhibitors resemble molecules that form chemical aggregates, which are known to inhibit many proteins. Eight known chemical aggregators inhibited amyloid formation of the yeast and mouse prion proteins Sup35 and recMoPrP in a manner characteristic of colloidal inhibition. Similarly, three known anti-amyloid molecules inhibited b-lactamase in a detergent-dependent manner, which sugg...

BACKGROUND Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a novel marker and participant in vascular inflammation. Inflammation also is associated with coronary atherosclerosis. We tested the hypothesis that local coronary production of Lp-PLA2 is enhanced in patients with early coronary atherosclerosis and associated with local endothelial function. METHODS AND RESULTS Coronary angiogr...

Background: Male infertility is responsible for approximately 50% of infertility in the world. Reactive oxygen species (ROS) is one of the causative agents of infertility in males which effects on sperm quality and function. In this study, the effects of oxidative stress induced by tertiary-butyl hydroperoxide (TBHP) were investigated on sperm quality, testis tissue and miRNAs expression. Mater...

The primary purpose of this scientific work is to study the specifics initiating criminal cases on crimes under Articles 198, 199, 199.1, 199.2, 199.3, and 199.4 Criminal Code Russian Federation following current legislation. Using methods analysis legislation, published works subject, legal comparison, practical activities investigation bodies, article developed provisions recommendations, whi...

STATEMENT OF PROBLEM Hard denture acrylic resins must maintain color stability to remain esthetic. PURPOSE The purpose of this in vitro study was to measure the color stability of denture resins subjected to staining agents and cleaned with denture cleansers MATERIAL AND METHODS Forty-five disks (10-mm diameter, 2-mm thick) fabricated from 3 denture resins (light polymerized Eclipse; heat p...

Background: Foot-and-mouth disease (FMD) is a highly contagious and economically important disease that affects cloven-hoofed animals worldwide. In recent years, a series of outbreaks of FMD have occurred in many countries. Recombinant protein synthesis incorporating protective B- and T-cell epitopes are candidates for new safer and more effective (FMD) vaccines that have potential to provide p...

BACKGROUND The rehabilitative dental care is important for maintaining adequate nutrition, guarding against wasting syndrome and malnutrition among human immunodeficiency virus (HIV)-infected individuals. AIM The aim of this study is to determine the Nigerian dental technology students' knowledge and misconceptions about HIV infection and their willingness to care for HIV-infected patients. ...

abstract background and purpose:the main objectives of this research were to evaluating the application of electrocoagulation process for 198 dye from the aqueous phase and determining the optimum operating conditions to the dye removal using aluminum and iron electrodes. materials and methods:the present study was conducted in bench-scale. the spectrophotometer dr 5000 was used to determine th...

[This corrects the article DOI: 10.3389/fevo.2014.00051.][This corrects the article on p. 198 in vol. 5, PMID: 25071828.].

OBJECTIVE Eosinophilic esophagitis (EoE) can be difficult to diagnose. We aimed to evaluate whether a gene expression score could differentiate adult EoE cases from non-EoE controls and to determine whether scores normalized after treatment for EoE. METHODS We analyzed prospectively collected esophageal biopsies from EoE patients (diagnosed as per consensus guidelines and after a proton pump ...