Assessing the retention of cell therapies following implantation is vital and often achieved by labelling cells with 2'-[18F]-fluoro-2'-deoxy-D-glucose (18F-FDG). However, this approach is limited by local retention of cell-effluxed radiotracer. Here, in a preclinical model of critical limb ischemia, we assessed a novel method of cell tracking using 3'-deoxy-3'-L-[18F]-fluorothymidine (18F-FLT)...

BACKGROUND 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) and PET/CT have become two of the most powerful tools for malignant lymphoma exploration, but their diagnostic role in primary central nervous system lymphoma (PCNSL) is still disputed. The purpose of our study is to identify the usefulness of 18F-FDG PET and PET/CT for detecting PCNSL. RESULTS A total of 129 patie...

Hellenic Journal of Nuclear Medicine January April 2011 www.nuclmed.gr 2 Figures 2 and 3. 131I-SPET study (Fig. 2) further clarified these foci in both kidneys. 18F-FDG-PET scan (Fig. 3) done on a separate day revealed abnormal foci of 18F-FDG uptake in the lower poles of both kidneys, corresponding to the foci seen on post treatment 131I-SPET. In the 18F-FDG-PET image, the foci can be well vis...

OBJECTIVES Several studies using 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) or diffusion tensor imaging (DTI) have found both temporal and extratemporal abnormalities in patients with mesial temporal lobe epilepsy with ipsilateral hippocampal sclerosis (MTLE-HS), but data are lacking about the findings of both techniques in the same patients. We aimed to determine whether...

objective(s): expression of her2 in gastric carcinoma has direct prognostic and therapeutic implications in patient management. the aim of this study is to determine whether a relationship exists between standardized uptake value (suv) and expression of her2 in advanced gastric carcinoma. methods: we analyzed the 18f-fdg pet/ct results of 109 patients that underwent gastrectomy for advanced gas...

A 44-year-old female patient presented symptoms and laboratory data consistent with a Cushing’s syndrome. Endocrine investigations and negative pituitary imaging were suggestive of ectopic ACTH secretion. Therefore, the patient underwent fluorine18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) and somatostatin receptor scintigraphy (SRS) searching for the ...

conclusions 18 f fdg pet/ct is a valuable imaging tool in initial and subsequent treatment strategy in patients with breast cancer by providing additional nodal and distant metastasis and may have the promising future potential to be as the imaging modality of choice for accurate assessment of disease extension in breast cancer in routine clinical practice. methods of a total 256 patients with ...

metastatic tumors to the heart unlike primary cardiac tumors are not rare. despite its frequency, cardiac metastasis is commonly detected only during autopsy as the symptoms of disseminated metastasis prevail over symptoms caused by cardiac metastasis and hence is overlooked most of the time. tumors more commonly found metastasizing to the heart are malignancies of lung, breast, esophagus, lymp...

The aim of this study was to evaluate whether the development of hepatocellular carcinoma (HCC) in murine models resembles tumor progression in humans, using non‑invasive molecular imaging methods. Murine HCC models were generated by treating mice with diethylnitrosamine (DEN) or by the transgenic expression of hepatitis B virus X (HBx) protein (HBx-Tg model). Tumor development was detected usi...

BACKGROUND This study investigated the relationships between background intestinal uptake on 18F-FDG PET and cardio-metabolic risk (CMR) factors. METHODS A total of 326 female patients that underwent 18F-FDG PET to determine the initial stage of breast cancer were enrolled. None of the patients had history of diabetes or hypertension. The background intestinal uptake on PET was visually grade...