pH-responsive megagates have been fabricated around mesoporous silica material SBA-15 in order to mechanize the mesopores. These megagates remain closed in neutral conditions, but open at pH 5. The capping components of the megagates were designed to be capable of controlling pores up to 6.5 nm in diameter. Selectivity of payloads with different sizes can be achieved through the use of differen...

IL-15 is critical for generation of multiple lymphoid subsets. Recent data have demonstrated a unique aspect of responses to IL-15, in that cells bearing the IL-15Ralpha chain can bind soluble IL-15 and "transpresent" the cytokine to other cells, allowing the latter to respond to IL-15. However, it is unclear whether IL-15 is normally secreted and then becomes bound to surface IL-15Ralpha on by...

Interleukin-15/T(IL-15) is a growth factor that utilizes IL-2 receptor (IL-2R) components in addition to its private binding protein IL-15R(alpha) in T-cells. Here, we report that IL-15 induces mast cell proliferation in the absence of IL-2R alpha and beta. Using transfectants of these cells with a cytoplasmic-truncated mutant of gamma(c), we demonstrated that IL-15 signaling in mast cells does...

Two new diterpenes namely verbenacine (1) and salvinine (2) have been isolated from the aerial parts of Salvia verbenaca. Their structures have been elucidated on the basis of chemical and spectral data as 3alpha-hydroxy-19-carboxykaur-15-ene and 19-hydroxy-12,14-dioxo labda-15,17-diene.

[This corrects the article DOI: 10.1371/journal.pone.0184190.].

The reaction of MgCl(2), NiCl(2), and Na(2)(i-mnt) (i-mnt is 1,1-dicyano-thene-2,2-dithiol-ate) with 15-crown-5 (15-C-5) leads to an infinite chain polymer, {[NiMg(2)(C(4)N(2)S(2))(2)(C(10)H(20)O(5))(2)]Cl(2)}(n) or {[Mg(15-C-5)](2)[Ni(i-mnt)(2)]Cl(2)}(n), which consists of two [Mg(15-C-5)](2+) complex cations, one [Ni(i-mnt)(2)](2-) complex anion and two Cl(-) ions per formula unit. In the [Ni...

Problem statement: Santa Barbara Amorphous (SBA-15) is significant mesoporous silica with exclusive and important properties of highly ordered mesopores, hydrothermally stable and thick wall, profusely large surface area and huge pore volume which render it as promising catalyst for wide applications. However, the purely siliceous SBA-15 which lacks of acidity characteristic hinders its ideal c...

Over the past decade, cloud services emerged as one of the most promising technologies in IT. Since cloud computing allows improving the quality of software and, at the same time, aims at reducing costs of operating software and hardware, more and more software is delivered as a service in the cloud. However, moving existing software applications to the cloud and making them behave as software ...