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Background: Rybp (Ring1 and YY1 binding protein) is a zinc finger protein which interacts with the members of the mammalian polycomb complexes. Previously we have shown that Rybp is critical for early embryogenesis and that haploinsufficiency of Rybp in a subset of embryos causes failure of neural tube closure. Here we investigated the requirement for Rybp in ocular development using four in vi...

Traditional ways of validating and verifying software include testing/simulation and theorem proving. Testing may start as soon as the first prototype exists. No knowledge of a specialised formalism is required. Testing is based on a collection of test cases, correctness is assured for each test case. The number of test cases may grow exponentially with the number of input variables. Therefore,...

Introduction: As spacecraft designs converge toward miniaturization and with the volumetric and mass constraints placed on avionics, programs will continue to advance the “state of the art” in spacecraft systems development with new challenges to reduce power, mass and volume. Although new technologies have improved packaging densities, a total system packaging architecture is required that not...

distances Different distances between two given vectors Description These functions are used for calculating different distances between two given vectors. Thus, L1.dist calculates the L1 distance, cosin.dist calculates the cosine distance, euclidian.dist computes the Euclidian distance, and rank.cor.dist computes the rank correlation distance. The vectors have to have same length. When using r...