نتایج جستجو برای: 124 triazin 5 one 6 azauracil

تعداد نتایج: 3451822  

Journal: :Molecules 2016
Christos P Constantinides Andrey A Berezin Georgia A Zissimou Maria Manoli Gregory M Leitus Panayiotis A Koutentis

3-Adamantyl-1-phenyl-1,4-dihydrobenzo[e][1,2,4]triazin-4-yl (4) crystallizes as chains of radicals where the spin bearing benzotriazinyl moieties are isolated from each other. Magnetic susceptibility studies in the 5-300 K temperature region indicate that radical 4 demonstrates typical paramagnetic behavior stemming from non-interacting S = ½ spins.

Journal: :International journal of oncology 2008
Matthias Kapischke Tim Fischer Katrin Tiessen Harald Tschesche Hans-Peter Bruch Holger Kalthoff Marie-Luise Kruse

Matrix metalloproteinases (MMPs) play a central role in tissue maintenance, inflammation and during tumour invasion and metastasis. The impact of MMPs in cancer has encouraged the development of novel MMP-inhibitors without adverse effects on the cell viability. We describe here the synthesis and characterisation of a triazine-derivative as a highly potent MMP-inhibitor. The new compound Triazi...

Journal: :Applied microbiology 1968
R W Sidwell G J Dixon S M Sellers F M Schabel

The in vivo anti-influenza virus and antivaccinia virus activity of 156 biologically active compounds was determined. One of two criteria was used for evaluating activity against the influenza virus. The criteria were increase in survivor number and mean survival time, and reduction in virus-induced lung consolidation in treated, infected Swiss mice. Increase in survivor number and mean surviva...

Journal: :Gastroenterology 2013
Georgios Koukos Christos Polytarchou Jess L Kaplan Alessio Morley-Fletcher Beatriz Gras-Miralles Efi Kokkotou Mariah Baril-Dore Charalabos Pothoulakis Harland S Winter Dimitrios Iliopoulos

BACKGROUND & AIMS Altered levels and functions of microRNAs (miRs) have been associated with inflammatory bowel diseases (IBDs), although little is known about their roles in pediatric IBD. We investigated whether colonic mucosal miRs are altered in children with ulcerative colitis (UC). METHODS We used a library of 316 miRs to identify those that regulate phosphorylation of signal transducer...

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