It is shown that for every b > a > 0 and for every two independent identically distributed real random variables X and Y Prob[|X − Y | ≤ b] < (2db/ae − 1)Prob[|X − Y | ≤ a]. This is tight for all admissible pairs a, b. Higher dimensional extensions are also considered.

Radiation exposure to the kidney from iodine-123 orthoiodohippurate ([123I]OIH) and any associated [124I]OIH contamination may vary by a factor of several hundred depending upon the health of the kidney. Calculations of kidney dose were made for patients with the following renal states: normal, acute tubular necrosis (ATN), obstruction, and renal transplant. The dosimetry was based on a minimum...

High-risk human papillomavirus (HPV) E6 protein induces telomerase activity through transcriptional activation of hTERT, the catalytic subunit of telomerase. HPV type 16 (HPV16) E6 interacts with two splice variants of NFX1 to increase hTERT expression. NFX1-91 is a transcriptional repressor of hTERT that is polyubiquitinated and targeted for degradation by HPV16 E6 in concert with E6-associate...

OBJECTIVE To investigate whether a serotonin-to-dopamine terminal ratio is related to the appearance of dyskinesias in patients with Parkinson disease (PD). METHODS Twenty-eight patients with idiopathic PD (17 with levodopa-induced dyskinesias [LIDs], 11 without dyskinesias) and 12 age-matched healthy controls were studied with PET and 5[(11)C]-3-amino-4-(2-dimethylaminomethylphenyl-sulfanyl)...

abstract- studies of the epidemiology of civilian vascular trauma in developing countries are rather few. this is a prospective study of our experience with vascular trauma in a referral university hospital in tehran, iran. the aim was to study the etiology, pattern of injuries and the mortality and morbidity rates due to vascular trauma in our population. in this cross-sectional study, all tra...

BACKGROUND There is a well-recognized need for a new generation of single photon emission computed tomography (SPECT) perfusion tracers with improved myocardial extraction over a wide flow range. Radiotracers that target complex I of the mitochondrial electron transport chain have been proposed as a new class of myocardial perfusion imaging agents. 7-(Z)-[(125)I]iodorotenone ((125)I-ZIROT) has ...

INTRODUCTION Tumour-associated urokinase plasminogen activator (uPA) is a critical marker of invasion and metastasis, and it is recognised as having strong prognostic relevance as well as being a therapeutic target. The specific uPA inhibitor plasminogen activator inhibitor type-2 (PAI-2, SerpinB2) specifically targets cell bound uPA and is internalised. Furthermore, preclinical studies have es...

We enumerate permutations which have exactly r 123-patterns and s 132patterns where r + s ≤ 2. We also give a new bijection between the ordered trees on n+1 vertices and 123-avoiding permutations of length n. We define the weight of ordered trees so that the bijection becomes weight-preserving, and find the generating function, in the form of a continued fraction, of 123-avoiding permutations o...