With the spread of parallel architectures throughout all areas of computing, task-based parallelism is an increasingly commonly employed programming paradigm, due to its ease of use and potential scalability. Since C++11, the ISO C++ language standard library includes support for task parallelism. However, existing research and implementation work in task parallelism relies almost exclusively o...

Although RCU is gaining significant use both within and outside of the Linux kernel, there are no know high-performance implementations of memory order consume loads in any C11 or C++11 environments. This situation suggests that some change is in order: After all, if the standard does not support this use case, the corresponding users can be expected to continue to exploit whatever implementati...

Apolipoprotein A-I (apo A-I), the major apolipoprotein in human high density lipoproteins, is involved in the disease atherosclerosis. Cloned apo A-I cDNA (pA1-3) was used as a probe in chromosome mapping studies to detect the human apo A-I structural gene sequence in human-Chinese hamster cell hybrids. Southern blot analysis of 13 hybrids localized the gene to human chromosome 11. Confirmation...

We consider the search for a maximum likelihood assignment of hidden derivations and grammar weights for a probabilistic context-free grammar, the problem approximately solved by “Viterbi training.” We show that solving and even approximating Viterbi training for PCFGs is NP-hard. We motivate the use of uniformat-random initialization for Viterbi EM as an optimal initializer in absence of furth...

In the presented study the ribavirin-TP--an established inhibitor of the NTPase activity of the superfamily NTPase/helicases II--was investigated as an inhibitor of the unwinding activity of the hepatitis C virus (HCV) NTPase/helicase. The kinetics of the reaction revealed that ribavirin-TP reduces the turnover number of the helicase reaction by a mechanism that does not correspond to that of t...