Agitation is common across neuropsychiatric disorders and contributes to disability, institutionalization, diminished quality of life for patients their caregivers. In 2015 IPA convened a transparent process build consensus definition agitation agreement on what elements should be included in the syndrome that resulted publication provisional guidelines. (Cummings et al, 2015) 2020-2021 year, t...

In metastatic colorectal cancer (mCRC) the choice of treatment should take into account characteristics tumor and patient, as well its efficacy tolerability. The RECOURSE study demonstrated that presence low burden indolent disease has an impact on progression-free (PFS) overall (OS) survival patients treated with trifluridine/tipiracil (TAS-102). Retrospective included mCRC undergoing TAS-102 ...