Prominent DNA gyrase-mediated cleavage sites, induced by oxolinic acid, occur at specific, but infrequent, locations on the Escherichia coli chromosome. These sites, which we call toposites, may represent high affinity DNA gyrase binding sites or may mark chromosomal regions that accumulate superhelical stress. Toposites are usually grouped in 5 to 10 kb clusters that are mostly 50 to 100 kb ap...

0 10 20 30 −50 0 50 100 150 r (mm) U (m /s ) x/DB = 0.2 0 10 20 30 −10 −5 0 5 10 r (mm) V (m /s ) x/DB = 0.2 0 10 20 30 −50 0 50 100 150 r (mm) U (m /s ) x/DB = 0.6 0 10 20 30 −10 −5 0 5 10 r (mm) V (m /s ) x/DB = 0.6 0 10 20 30 −50 0 50 100 150 r (mm) U (m /s ) x/DB = 1.4 0 10 20 30 −10 −5 0 5 10 x/DB = 1.4 r (mm) V (m /s ) Experiment Raman et al. LES/HPDF Liu et al. Merci et al. Fig. 1. Mean ...

The spatial variation in vector acoustic intensity has been calculated between 100 and 3000 Hz near a high-performance military aircraft. With one engine of a tethered F-22A Raptor operating at military power, a tetrahedral intensity probe was moved to 27 locations in the geometric near and mid-fields to obtain the frequency-dependent intensity vector field. The angles of the maximum intensity ...

S100P protein consists of 95 amino acids with a molecular weight of 10.4 kDa. S100P is a Ca binding protein that belongs to S100 family ("Soluble in 100% saturated solution with ammonium sulfate") which was first isolated from human placenta and is therefore designated as "P". S100 family includes at least 26 members, which are thought to be expressed only in vertebrates and are present in a ti...

We present a simple, but expressive type system that supports strong updates—updating a memory cell to hold values of unrelated types at different points in time. Our formulation is based upon a standard linear lambda calculus and, as a result, enjoys a simple semantic interpretation for types that is closely related to models for spatial logics. The typing interpretation is strong enough that,...

There is a large amount of information that can be extracted automatically from social media messages. Of particular interest are the topics discussed by the users, the opinions and emotions expressed, and the events and the locations mentioned. This work focuses on machine learning methods for detecting locations from Twitter messages, because the extracted locations can be useful in business,...

The orthocentroidal circle of a non-equilateral triangle has diameter GH where G is the centroid and H is the orthocenter. We show that the Fermat, Gergonne and symmedian points are confined to, and range freely over the interior disk punctured at its center. The Mittenpunkt is also confined to and ranges freely over another punctured disk, and the second Fermat point is confined to and ranges ...

Harnessing the latent knowledge present in geospatial trajectories allows for the potential to revolutionise our understanding of behaviour. This paper discusses one component of such analysis, namely the extraction of significant locations. Specifically, we: (i) present the Gradient-based Visit Extractor (GVE) algorithm capable of extracting periods of low mobility from geospatial data, while ...

We present a bootstrapping approach to infer new proteins, locations and protein-location pairs by combining UniProt seed proteinlocation pairs with dependency paths from a large collection of text. Of the top 20 system proposed protein-location pairs, 18 were in UniProt or supported by online evidence. Interestingly, 3 of the top 20 locations identified by the system were in the UniProt descri...

a r t i c l e i n f o JEL classification: F12 F15 R11 R12 Keywords: Heterogeneous taste and quality Spatial selection Economic geography Agglomeration Home market effect In this paper, we develop an economic geography model in which firms sell product varieties with heterogeneous demands. We show that firms that sell products with higher demand choose to establish their plants in larger countri...