The phytocomponent p-hydroxycinnamic acid (HCA) has been shown to have a stimulatory effect on bone formation and an inhibitory effect on bone resorption in rat femoral tissues in vitro. The preventive effect of HCA on bone loss induced in streptozotocin (STZ)-diabetic rats was investigated in vivo. Rats received a single subcutaneous administration of STZ (6.0 mg/100 g body weight), and then t...

BACKGROUND To evaluate the concept of critical illness-related corticosteroid insufficiency (CIRCI) by studying the clinical significance, in terms of risk factors and outcome, of changes in the cortisol response to repeated adrenocorticotropic hormone (ACTH) testing in the course of critical illness. PATIENTS AND METHODS In a retrospective study in a medical-surgical intensive care unit (ICU...

Abstract The aim of the work was to compare κ-carrageenan and ι-carrageenan (in concentrations 0.025–0.150 g/100 g) application cream desserts (dry matter content 44 g/100 g fat 38.5 g/100 g) evaluate their viscoelastic properties sensory quality. Sample were monitored during 28 d (6 ± 2 °C). During storage a slight decrease in pH samples monitored. Furthermore, increasing addition κ- resulted ...

the purpose of this study was to develop a new monolithic matrix tablet to completely deliver glipizide in a zero order manner over a sustained period. two approaches were examined using drug in a formulation that contain polymer like hydroxylpropyl methyl-cellulose k 100 (hpmck) and eudragit l 100. the granules were prepared by wet granulation method and thereby formulated as f-1, f-2. f-3 and...