The development of a Ni(II) (S)-Tol-BINAP-catalyzed enantioselective alkylation of N-acylthiazolidinethiones with trimethyl orthoformate is described. The reaction is general with respect to the thiazolidinethione, providing the desired adducts in good to excellent yield and with high levels of enantioselectivity (11 examples, 51-92% yield, 90-99% ee). The products are readily converted into a ...

The effect of some unsubstituted aromatic amines and their oand p-hydroxylated derivatives on isolated rat-liver mito chondria has been studied. The o-hydroxylated amines inhibited oxygen uptake in the presence of nicotinamide adenine dinucleotide-dependent respiratory substrates. Of the other compounds only l-amino-4-naphthol inhibited oxygen uptake. The Buccinate oxidase system was inhibited ...

In the crystal structure of the title cocrystal, 2C(24)H(18)ClNO(2)·C(6)H(12)N(2), the 1,4-diaza-bicyclo-[2.2.2]octane mol-ecule is located on a twofold rotation axis and linked to the two triaryl-imine mol-ecules by O-H⋯N hydrogen bonds, forming a 2:1 aggregate. C-H⋯Cl inter-actions are also observed. In the triaryl-imine mol-ecule, the naphthalene ring system makes dihedral angles of 80.39 (6...