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Objective(s): It is generally believed that the inflammatory response in bone marrow mesenchymal stem cells (BMSCs) transplantation leads to poor survival and unsatisfactory effects, and is mainly mediated by cytokines, including interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α). In this study, we explored the mechanisms underlying the TNF-α-induced inflammatory ...

Background and Aims: Plants as medicines have always played a vital role in human life. Tumor necrosis factor alpha (TNF)-α is one of the macrophage-derived inflammatory cytokine with pleotropic effects in the inflammation process. Some studies have been demonstrated that some of the Echinops species have anti-inflammatory activity. In fact, Echinops lasilepis is introduced as one of the ...

Adipocyte tissue inflammation orchestrates the occurrence and development of diseases induced by obesity. Here, effects Lagerstroemia speciosa (L.) Pers total flavonoids (LTF) on TNF-α-induced insulin resistance (IR) inflammatory response in 3T3-L1 adipocytes underlying mechanisms were studied. Cell glucose uptake test confirmed that TNF-α could induce IR adipocytes. The sensitivity to was incr...

ضارمأب ةباصلإا مدعو نسلا ةثادح نأ جئاتنلا ترهظأ :جئاتنلا ةيبلقلا ضارملأاو ،مدلا طغض عافتراو ،يركسلاك( ىرخأ ـب ةباصلإا نم مايأ ةعبس نوضغ يف جلاعلا يقّلتو )ةيئاعولا تاذ ةيعمس تاطيطخت دوجوو لدتعُحلما عمسلا نادقْفو ،ISSHL لضفأ ةقيرطب عمسلا ةداعتسا يف تمهاس ،ةدعاص تاءانحنا ةيقنلا ةمغنلا عمس سايق غلبو .ةيئاصحلإا ةيحانلا نم ريثكب ،طسوتلما يف لبيسيد 23.9 ± 67.8 رملأا لوأ يف )PTA( و لبيسيد 51.6±28.7 ىلإ ني...