نتایج جستجو برای: 0235 and 043
تعداد نتایج: 16827686 فیلتر نتایج به سال:
New drugs are required to counter the tuberculosis (TB) pandemic. Here, we describe the synthesis and characterization of 1,3-benzothiazin-4-ones (BTZs), a new class of antimycobacterial agents that kill Mycobacterium tuberculosis in vitro, ex vivo, and in mouse models of TB. Using genetics and biochemistry, we identified the enzyme decaprenylphosphoryl-beta-d-ribose 2'-epimerase as a major BTZ...
An abundance analysis for the carbon-enhanced, extremely iron-poor ([Fe/H]∼ −3.5) star CS 29498–043 has been obtained using new high-resolution, high signalto-noise spectra from the Subaru Telescope. The [O I] forbidden line at 6300 Å and the O I triplet feature at 7771-7776 Å are both clearly detected. The overabundance of oxygen is significant ([O/Fe]> 2). In addition, Na, Co, and Ni abundanc...
An abundance analysis for the carbon-enhanced, extremely iron-poor ([Fe/H]∼ −3.5) star CS 29498–043 has been obtained using new high-resolution, high signalto-noise spectra from the Subaru Telescope. The [O I] forbidden line at 6300 Å and the O I triplet feature at 7771-7776 Å are both clearly detected. The overabundance of oxygen is significant ([O/Fe]> 2). In addition, Na, Co, and Ni abundanc...
The effect of external as well as internal bremsstrahlung radiation in H ! ZZ ! 4e channel is studied in full detector simulation. A method is proposed for external and internal bremsstrahlung recovery, allowing us to use 95% of electrons within j E=pgen 1 j 0.2. It is shown that traditional E=p and isolation cuts can be implemented with 90% efficiency, but that precise mass reconstruction is a...
BACKGROUND Myocardial injury detected by cardiac troponin I and T (cTnI and cTnT) in cardiac disease is associated with increased risk of death in humans and dogs. HYPOTHESIS Presence of myocardial injury predicts long-term death in cats with hypertrophic cardiomyopathy (HCM), and ongoing myocardial injury reflects change in left ventricular wall thickness over time. ANIMALS Thirty-six cats...
BACKGROUND & OBJECTIVES R proteins were first identified by Lancefield in group B Streptococcus (GBS) as resistant to trypsin at pH8 and sensitive to pepsin at pH2. The R4 protein found predominantly in type III and some type II and V invasive isolates conforms to these criteria. The Rib protein, although structurally and epidemiologically similar to R4, was reported as resistant to both protea...
Long-term supplementation with conjugated linoleic acid (CLA) reduces body fat mass (BFM) and increases or maintains lean body mass (LBM). However, the regional effect of CLA was not studied. The study aimed to evaluate the effect of CLA per region and safety in healthy, overweight and obese adults. A total of 118 subjects (BMI: 28-32 kg/m2) were included in a double blind, placebo-controlled t...
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