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Rhizome-rooted alfalfa (Medicago sativa L.) is an excellent forage for establishing grazing and ecological grasslands, requiring a high stable yield. Studying the genetic physiological basis of expression biomass traits essential improving production performance in rhizome-rooted alfalfa. We analyzed mass photosynthetic indices improved progenies (RSA−01, RSA−02, RSA−03), parental “Qingshui” (C...
OBJECTIVES HLA-C*07:359 is a low-incidence allele in the human leukocyte antigen (HLA)-C locus. The objective of this study is to report the ethnicity and haplotypes of HLA-C*07:359 that were found during an analysis of Taiwanese unrelated bone marrow hematopoietic stem cell donors. MATERIALS AND METHODS A sequence-based typing method was employed to confirm low-incidence al-leles. Polymerase...
Pour élucider les principes qui gouvernent la complexité en biologie, la modélisation bioinformatique doit dépasser les explications ad hoc et faire émerger de nouveaux concepts abstraits [HUA 01]. Cela impose de comprendre la structure des systèmes biologiques, la dynamique de ces systèmes et les méthodes de mise au point de modèles pour prendre en compte les propriétés observées [KIT 02, WOL ...
Tapasin discriminates peptide-human leukocyte antigen-A*02:01 complexes formed with natural ligands.
A plethora of peptides are generated intracellularly, and most peptide-human leukocyte antigen (HLA)-I interactions are of a transient, unproductive nature. Without a quality control mechanism, the HLA-I system would be stressed by futile attempts to present peptides not sufficient for the stable peptide-HLA-I complex formation required for long term presentation. Tapasin is thought to be centr...
OBJECTIVE The present study aimed to explore the associations between food away-from-home (FAFH) consumption and body weight outcomes among Chinese adults. DESIGN FAFH was defined as food prepared at restaurants and the percentage of energy from FAFH was calculated. Measured BMI and waist circumference (WC) were used as body weight outcomes. Quantile regression models for BMI and WC were perf...
Background: Distal tibial fractures including tibial pilon present a challenge as to their best method of management due to subcutaneous location of larger portion of tibia, paucity of soft tissue coverage and precarious blood supply of distal leg. MIPO (Minimal invasive plating osteosynthesis) has evolved as a newer concept to treat distal tibial fractures with minimal articular comminution an...
PURPOSE We performed a phase I trial to investigate the safety, clinical responses, and Wilms' tumor 1 (WT1)-specific immune responses following treatment with dendritic cells (DC) pulsed with a mixture of three types of WT1 peptides, including both MHC class I and II-restricted epitopes, in combination with chemotherapy. EXPERIMENTAL DESIGN Ten stage IV patients with pancreatic ductal adenoc...
Pregnancy-associated plasma protein-A (PAPPA), also known as pappalysin, is a member of the insulin-like growth factor (IGF) family. PAPPA acts as a protease, cleaving IGF inhibitors, i.e., IGF binding proteins (IGFBPs), thereby setting free IGFs. The insulin/IGF-axis is involved in cancer in general and in Ewing sarcoma (ES) in particular. ES is a highly malignant bone tumor characterized by e...
The article presents the results of studying black currant varieties collection Kokinsky control station FSBSI FRC for Horticulture (Bryansk region) winter hardiness, resistance to Sphaerotheca, and gall mite in order create new initial forms based on selected genotypes, characterized by a high level adaptation their inclusion breeding work improve crop assortment. best combinations crosses (Ga...
Background: Human leukocyte antigen (HLA) gene is a highly polymorphic region. HLA typing is required to match patients and donors for transplantation; therefore, development of HLA registries is necessary for finding HLA match donors. HLA system is highly informative, and numerous studies have been conducted on HLA allele distribution in different populations. Methods: In this study,...
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