We would like to raise a concern regarding the mathematica l modelling study by Brooke Nichols and colleagues, which looked at the cost-effectiveness of preexposure prophylaxis (PrEP) for HIV-1 prevention in the Netherlands. Specifically, we have found that we are unable to replicate their results using the methodology described in their paper. In their modelling study the authors divided the p...

OBJECTIVE To describe the burden of otitis media (OM) among American Indian and Alaska Native (AI/AN) children. METHODS OM morbidity among AI/AN younger than 5 years was evaluated using OM-associated outpatient visit and hospitalization rates. These rates were compared with outpatient and hospitalization rates for the general US population of children younger than 5 years. AI/AN children who ...

We consider the history of certain modular elements: Op-tiles, Kufic tiles, and key-patterns, which occur as ornamental archetypes from Paleolithic times until the present. Paleolithic ornaments We have found that the oldest examples of ornamentation in Paleothic art were from Mezin (Ukraine) dated to 23 000 B.C. Note that 23 000 years is a time period ten times longer than the complete written...

X-ray spectra of a significant fraction of cooling flow (CF) clusters of galaxies indicate the presence of large columns of " cold " absorbing gas. The physical nature of the absorbing medium remains a mystery. Searches for H I absorption using the 21 cm hyperfine structure line yielded null results in most cases. The purpose of this contribution is to point out that the Lyman α absorption cros...

Modeling the reliability of distributed systems requires a good understanding of the reliability of the components. Careful modeling allows highly fault-tolerant distributed data applications to be constructed at the least cost. Failure and repair rates of components are often assumed to be exponentially distributed. This hypothesis is testable for failure rates, though the process of gathering...

How can we maintain a dynamic profile capturing a user’s reading interest against the common interest? What are the queries that have been asked 1, 000 times more frequently to a search engine from users in Asia than in North America? What are the keywords (or tags) that are 1, 000 times more frequent in the blog stream on computer games than in the blog stream on Hollywood movies? To answer su...

Sweden's compulsory addiction system treats individuals with severe alcohol and narcotics use disorders. Merging data from three national level register databases of those sentenced to compulsory care from 2001 to 2009 (n=4515), the aims of this study were to: (1) compute mortality rates to compare to the general Swedish population; (2) identify leading cause of mortality by alcohol or narcotic...