background & aim: singhnad guggulu is a traditional ayurvedic formula for detoxifying and rejuvenating the joints. the present study was to investigate the α-amylase inhibition and antioxidant activities of aqueous extract of singhnad guggul (aesg). experimental: α-amylase inhibition assay by dinitro-salicylic acid method and antioxidant activity by ferric chelating and ferrous reducing ass...

The phytochemical investigation of Muehlenbeckia tamnifolia, collected in Loja-Ecuador, led to the isolation of nine known compounds identified as: lupeol acetate (1); cis-p-coumaric acid (2); lupeol (3); β-sitosterol (4) trans-p-coumaric acid (5); linoleic acid (6) (+)-catechin (7); afzelin (8) and quercitrin (9). The structures of the isolated compounds were determined based on analysis of NM...

BACKGROUND Hyperglycaemia is a salient feature of poorly controlled diabetes mellitus. Rate of protein glycation is increased with hyperglycaemia leading to long term complications of diabetes. One approach of controlling blood glucose in diabetes targets at reducing the postprandial spikes of blood glucose. The objectives of this study were to assess the in vitro inhibitory effects of Costus s...

Background & Aim: Singhnad Guggulu is a traditional Ayurvedic formula for detoxifying and rejuvenating the joints. The present study was to investigate the α-amylase inhibition and antioxidant activities of aqueous extract of Singhnad Guggul (AESG). Experimental: α-Amylase inhibition assay by dinitro-salicylic acid method and antioxidant activity by ferric chelating and ferrous reducing assay....

In this study, Biarum bovei extract was used to produce bioactive peptides from wheat gluten protein and the biological functional properties of hydrolysates were determinated. The results showed that has its highest protease activity (7.3 U/mg protein) at 45 °C pH 5. Based on electrophoresis analysis, molecular weight hydrolysate < 10 kDa. F1 fraction had antioxidant in DPPH (65.85 ± 2.64 µmol...

The effect of cooking on starch hydrolysis, polyphenol contents, and in vitro α-amylase inhibitory properties of mushrooms (two varieties Russula virescens and Auricularia auricula-judae), sweet potato (Ipomea batatas), and potato (Solanum tuberosum) was investigated. The total, resistant, and digestible starch contents of the raw and cooked food samples (FS) ranged from 6.4 to 64.9; 0 to 10.1;...

in our previous study, we compared the two α-amylase enzymes from bacillus sp.kr8104, bka∆(n44) and bka∆(n44c193) which is the secreted form of it. the results indicated that the presence of 193 amino acids propeptide in the c-terminal of bka∆(n44) changed its enzymatic parameters like an uncompetitive inhibitor in comparison to bka∆(n44c193). in the present study, we cloned the dna sequence of...

CONTEXT Hyperglycemia is the hallmark of type 2 diabetes mellitus, and its prevention will go a long way in managing the disease and its associated complications. Reduction of postprandial hyperglycemia through retarding carbohydrates digesting enzymes is one of the major therapeutic approaches used in the management of diabetes. OBJECTIVE The aim of the present study was to investigate the a...

caused as lifestyle disease is increasing and has become something of a social problem in recent years. a-Glucosidase inhibitors, medicines that prevent elevation of postprandial blood glucose, can control blood glucose levels without depending on increased secretion of insulin and results in lowering the amount of insulin required after meals. A similar effect to that of these medicines can be...