BACKGROUND Screening of anal cancer in HIV-infected MSM with anal cytology results in high rates of false positive results and elevated burden of high-resolution anoscopies. High-risk HPV up-regulates p16 and Ki67 expression in epithelial cells. We assessed the usefulness of P16/Ki-67 immunostaining cytology for the diagnosis of precancerous anal lesions. METHODOLOGY Cross-sectional multicent...

The seminal work by Papanicolaou and Traut in studying the cells from precancerous and cancerous lesions of the cervical mucosa paved the way for oral cytology. Their work proved an effective tool for screening gynecologic malignant disease [ 1 ] . Initially, the use of oral cytology was limited to comparative studies of oral and cervical cytology, describing cytomorphological changes depending...

Papanicolaou tests are often repeated just before the procedure for women who have been referred for colposcopy. The validity and clinical usefulness of this practice, however, is unclear. We retrospectively assessed the value of repeated cytology in a cohort of 1,087 consecutive patients who underwent repeated Papanicolaou testing at first colposcopy. The repeated cytology was considered clini...

OBJECTIVE Our goals were to determine the added value of fine-needle aspiration biopsy (FNAB)-thyroglobulin (Tg) measurements over FNAB-cytology alone for diagnosing metastatic nodes, and to determine whether the ultrasound features of lymph nodes can be used to identify lymph nodes that may benefit from FNAB-Tg measurement in patients with papillary thyroid cancer. MATERIALS AND METHODS We r...

BACKGROUND/AIMS Small core biopsy samples can occasionally be obtained with conventional endoscopic ultrasonography-guided fine needle aspiration (EUS-FNA). Although most studies have focused on the cytological analysis of specimens, data regarding histological assessment is scarce. The aim of this study was to determine whether core biopsies by conventional EUS-FNA could increase the accuracy ...

small cell carcinoma of the urinary bladder (sccub) is an extremely rare bladder malignancy characterized by an aggressive clinical behavior. so, it is important to diagnose this high grade disease by urinary cytology. we report a case of sccub in an old man with chronic lymphocytic leukemia (cll) in remission, while bladder tumor was diagnosed by cytology. with this article, we aimed to review...

Objetive: to analyze whether ultrasonography with fine-needle aspiration cytology of an axillary suspicious node, in patients breast cancer, could help differentiate between low involvement the axilla (up 2 nodes macrometastasis) those high (more than lymph macrometastasis). Material and methods: A total 115 consecutive cancer 5 cm diameter), clinically negative pathologically positive axilla. ...

Cervical cytology is a screening tool that helps to categorize patients for their risk of cervical neoplasm depending on the degree of shift from normal cervical cytology and the amount of the abnormal change seen. Since the cervix is subject to hormonal effects, the clinical context (exogenous estrogens, pregnancy, etc.) should be considered when evaluating cervical cytology specimens. The fir...

BACKGROUND Currently, available data regarding previous cervical cytology and high-risk human papillomavirus (hrHPV) test results to detect invasive cervical cancer are limited and controversial in China. Therefore, this retrospective study in a population of Chinese women with invasive cervical carcinoma aimed to gain further insight into the roles of cytology and hrHPV testing in cervical can...