Considered an antidepressant and anti-anxiety agent, Hypericum perforatum affects multiple neurotransmitters in a non-competitive synergistic manner, and may have nootropic potential. We quantitatively reviewed the pre-clinical literature to examine if there is a cognitive-enhancing effect of H. perforatum in healthy rodents. Additionally, within these studies, we compared the effects observed ...

OBJECTIVES The John Henryism (JH) hypothesis suggests that, under adverse social and economic conditions, high-effort coping styles that reflect hard work and determination may contribute to elevated blood pressure. Results from tests of this hypothesis have been mixed, with variations by region, urban versus rural areas, race, gender, and age. The majority of studies reporting that socioeconom...

ss Open Acce Proceedings Genetic Analysis Workshop 15: gene expression analysis and approaches to detecting multiple functional loci Heather J Cordell*1, Mariza de Andrade2, Marie-Claude Babron3, Christopher W Bartlett4, Joseph Beyene5, Heike Bickeböller6, Robert Culverhouse7, L Adrienne Cupples8, E Warwick Daw9, Josée Dupuis8, Catherine T Falk10, Saurabh Ghosh11, Katrina A Goddard12, Ellen L G...

The relationship between law and morality represents a major theme in jurisprudence and is the subject-matter of this article. I shall focus on the use of the criminal law to enforce morality and, in particular, I shall consider whether an identifiable line can be drawn between moral standards that may properly be the subject of legal enforcement and those that may not. This issue was, of cours...

Bartholomew's Hospital, where he had trained towards the end of the long career of John Abernethy, who attracted large numbers of students to his lectures. He had begun his medical career in the 1820s (L.S.A. 1824, M.R.C.S. 1825) and subsequently gained an F.R.C.S. by examination in 1847, and an M.D. from the University of St Andrews in 1856, during the course of his medical practice in Yeovil.

OBJECTIVE Hypericum perforatum (St. John's Wort) has long been used in traditional medicine to treat a variety of internal and external ailments. The present study was done to evaluate the immumodulatory potentials of the hydroalcoholic extract of H. perforatum. MATERIALS AND METHODS Twenty male BALB/c-mice were randomly allocated in two equal groups and immunized with sheep red blood cells (...

BACKGROUND/OBJECTIVES This study was conducted to assess the potential of St. John's Wort (Hypericum perforatum) to prevent obesity and abnormalities in lipid metabolism induced by ovariectomy in a rat model without stimulatory activity on uterus. MATERIALS/METHODS Ovariectomized (OVX) rats were treated for 6 weeks with 70% ethanol extracts of Hypericum perforatum [HPEs: whole plant (WHPE) an...