نتایج جستجو برای: ژن nfkb
تعداد نتایج: 16591 فیلتر نتایج به سال:
The co-occurrence of the three disease entities, inflammatory bowel disease (IBD), colorectal cancer (CRC), type 2diabetes mellitus (T2DM) along with inflammation and dismicrobism has been frequently reported. Some authors have even suggested that dysbiosis could be the link through a molecular crosstalk of multiple inflammatory loops including TGFβ, NFKB, TNFα and ROS among others. This review...
Curcumin, a phytochemical isolated from curcuma plants which are used as coloring ingredient for the preparation of curry powder, has several activities which suggest that it might be an interesting drug for the treatment or prevention of cancer. Curcumin targets different pathways which are involved in the malignant phenotype of tumor cells, including the nuclear factor kappa B (NFKB) pathway....
o u rn a l o f C e ll S c ie n c e A novel mechanism of control of NFkB activation and inflammation involving A2B adenosine receptors Ying Sun, Yuanyuan Duan, Anna S. Eisenstein, Wenbao Hu, Adrien Quintana, Wai Kwan Lam, Yan Wang, Zhenguo Wu, Katya Ravid and Pingbo Huang* Division of Life Science, and State Key Laboratory of Molecular Neuroscience, Hong Kong University of Science and Technology...
Sir, Incontinentia pigmenti (IP) is an X-linked dominant trait that is intrauterine lethal for males. The disorder is caused by NEMO mutations involving the NFkB activation pathway (1). It is characterized by linear skin lesions and various defects of the central nervous system, the teeth and the eyes. The cutaneous lesions are arranged along the lines of Blaschko, reflecting functional X-chrom...
Ubiquitination plays a critical role in the activation of host immune responses to infection and serves as a signal for pathogen delivery to phagophores along the xenophagy pathway. We recently performed systematic ubiquitination site profiling of epithelial cells infected with Salmonella Typhimurium. Our findings specifically highlight components of the NFKB, membrane trafficking pathways and ...
This is a technical paper describing a variety of preliminary results from in vitro experiments, performed at national research institutions, investigating the bioactivity of a certain redox signaling compound, ASEATM, when placed in direct physical contact with living cells. Specific investigations include in vitro toxicity and antioxidant efficiencies of the master antioxidants glutathione pe...
Extranodal lymphomas of the mucosa-associated lymphoid tissue (MALT) account for approximately 8% of all non-Hodgkin’s lymphomas and comprises up to 50% of primary gastric lymphomas, however they can arise in virtually any extranodal site.1-3 Their histologic features are similar regardless of the site of origin.4 MALT lymphoma usually arises in mucosal sites where lymphocytes are not normally ...
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