Cannabinoids apparently act on inflammation through mechanisms different from those of agents such as nonsteroidal anti-inflammatory drugs (NSAIDs). As a class, the cannabinoids are generally free from the adverse effects associated with NSAIDs. Their clinical development thus provides a new approach to treatment of diseases characterized by acute and chronic inflammation and fibrosis. A concis...

Cissampelos pareira Linn. (Menispermaceae) widely distributed all over India and it is widely used for various kidney disorders. According to the Ayurveda, the kidneys are made up of the "Rakta" and "Meda" dhatus. Treating these two dhatus is also an effective way to treat the kidneys. The plant Cissampelos pareira Linn. is used to treat these two dhatus. This promotes us to undertake a study t...

Basic fibroblast growth factor (FGF2) belongs to the family of the heparin-binding growth factors (Basilico and Moscatelli, 1992). The single copy human FGF2 gene encodes multiple FGF2 isoforms with Mr ranging from 24,000 to 18,000 (Florkiewicz and Sommer, 1989). FGF2 isoforms are angiogenic in vivo and induce cell proliferation, protease production and chemotaxis in endothelial cells in vitro ...

This chapter provides three perspectives on feminist mentoring from two generations of faculty. After a brief review of the traditional mentoring and feminist/multicultural mentoring literatures, Meda Chesney-Lind begins the discussion with some thoughts on survival strategies that she has gleaned from decades of work in the academy. Her reflections on teaching, research, and service in the aca...

BACKGROUND It has been previously reported that melittin, the main ingredient of honey bee venom, has anticancer properties. However, there appears to be no earlier study focusing on the isolation of melittin from Iranian honey bee venom (Apis mellifera meda), and evaluation of its effect on cancerous cells. METHODS We isolated melittin using reversed-phase high performance liquid chromatogra...

Novel high-throughput analyses in molecular biology allow sensitive and rapid identification of disease-related genes and drug targets. We have used quantitative real-time reverse transcription-PCR reactions (n = 23000) to analyze expression of all human receptor tyrosine kinases (n = 56) in malignant tumors (n = 313) of different origins and normal control samples (n = 58). The different tumor...