Given an unlabeled protein sequence S and a known superfamily F, we wish to determine whether or not S belongs to F. We refer to F as the target class and the set of sequences not in F as the non-target class. In general, a superfamily is a group of proteins that share similarities in structure and/or function. If the unlabeled sequence S is detected to belong to F, then one can infer the struc...

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factors for airway remodelling in asthma manifested by a low post bronchodilator FEV1/ vital capacity ratio: a longitudinal population study from childhood to adulthood. Am J Respir Crit Care Med 2002;165:1480–8. 9 Covar RA, Spahn JD, Murphy JR, et al. Progression of asthma measured by lung function in the childhood asthma management program. Am J Respir Crit Care Med 2004;170:234–41. 10 Lazaar...