نتایج جستجو برای: ژن hlya

تعداد نتایج: 16132  

Journal: :The Journal of biological chemistry 1992
P Juranka F Zhang J Kulpa J Endicott M Blight I B Holland V Ling

The prokaryotic hlyB gene product is a member of a superfamily of ATP-binding transport proteins that include the eukaryotic multidrug-resistance P-glycoprotein, the yeast STE6, and the cystic fibrosis CFTR gene products (Juranka, P. F., Zastawny, R. L., and Ling, V. (1989) FASEB J. 3, 2583-2592). Previous genetic studies have indicated that HlyB is involved in the transport of the 107-kDa HlyA...

Journal: :Emerging infectious diseases 2002
Asis Khan Shinji Yamasaki Toshio Sato Thandavarayan Ramamurthy Amit Pal Simanti Datta Nandini Roy Chowdhury Suresh Chandra Das Asim Sikdar Teizo Tsukamoto Sujit Kumar Bhattacharya Yoshifumi Takeda Gopinath Balakrish Nair

We investigated the prevalence of Shiga toxin-producing Escherichia coli (STEC) in hospitalized diarrhea patients in Calcutta, India, as well as in healthy domestic cattle and raw beef samples collected from the city's abattoir. Multiplex polymerase chain reaction using primers specific for stx1 and stx2 detected STEC in 18% of cow stool samples, 50% of raw beef samples, and 1.4% and 0.6% of bl...

Journal: :The EMBO journal 2005
Jelena Zaitseva Stefan Jenewein Thorsten Jumpertz I Barry Holland Lutz Schmitt

The ABC transporter HlyB is a central element of the HlyA secretion machinery, a paradigm of Type I secretion. Here, we describe the crystal structure of the HlyB-NBD (nucleotide-binding domain) with H662 replaced by Ala in complex with ATP/Mg2+. The dimer shows a composite architecture, in which two intact ATP molecules are bound at the interface of the Walker A motif and the C-loop, provided ...

Journal: :Aquaculture Research 2021

In fish, bacteriosis has been widely linked with Aeromonas species, but co-infection by these bacteria little addressed. The aims of this study were to report on an outbreak disease in pirarucu Arapaima gigas caused and investigate experimental characterize resistance profile, virulence factors phenotypic molecular differentiation. Fish samples clinical signs collected used co-infection. bacter...

Journal: :Revista Argentina de microbiologia 2004
C Bidinost H A Saka O Aliendro C Sola G Panzetta-Duttari P Carranza J Echenique E Patrito J L Bocco

V. cholerae non-O1 non-O139 serogroups isolated from clinical and environmental sources in Córdoba, Argentina, were analyzed for the presence and expression of virulence genes. Most of the strains studied contained the genes toxR and hlyA, but lacked ctxA, zot, ace, tcpA and stn. The culture supernatants were tested for hemolytic and cytotoxic activity. The enterotoxic potential of the strains ...

Journal: :Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2002
Ming-Cheng Wang Chin-Chung Tseng Chiung-Yu Chen Jiunn-Jong Wu Jeng-Jong Huang

We studied the pathogenic role of host and Escherichia coli virulence factors in the development of E. coli bacteremia in patients with acute cholangitis (AC) or upper urinary tract infection (UTI). Isolates recovered from 75 adult patients consecutively admitted to the hospital with E. coli bacteremia caused by AC (n=24) or upper UTI (n=51) were evaluated, as were 30 fecal strains isolated fro...

2008
Mateus Matiuzzi da Costa Guilherme Drescher Franciele Maboni Shana Weber Sônia de Avila Botton Marilene Henning Vainstein Irene Silveira Schrank Agueda Castagna de Vargas

The present study determined the molecular and resistance patterns of E. coli isolates from urinary tract of swine in Southern of Brazil. Molecular characterization of urinary vesicle samples was performed by PCR detection of virulence factors from ETEC, STEC and UPEC. From a total of 82 E. coli isolates, 34 (38.63%) harbored one or more virulence factors. The frequency of virulence factors gen...

Journal: : 2022

Pelodiscus sinensis is a widespread species of soft-shelled turtle that commercially cultured in freshwater and prominently exploited as speciality food Vietnam. During the cultivation, there are distinctly recurrent epidemic diseases causing economically vast damage for farmers. In this research, we carried out isolation microorganisms from typical ulcers “ba dau” presenting on taken Nam Dinh ...

2012
Taru Lienemann Eeva Salo Ruska Rimhanen-Finne Kai Rönnholm Mari Taimisto Jari J. Hirvonen Eveliina Tarkka Markku Kuusi Anja Siitonen

Shiga toxin-producing Escherichia coli (STEC) is a pathogen that causes gastroenteritis and bloody diarrhea but can lead to severe disease, such as hemolytic uremic syndrome (HUS). STEC serotype O78:H(-) is rare among humans, and infections are often asymptomatic. We detected a sorbitol-fermenting STEC O78:H(-):stx(1c):hlyA in blood and fecal samples of a 2-week-old boy who had bacteremia and H...

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