نتایج جستجو برای: ژن he4
تعداد نتایج: 16408 فیلتر نتایج به سال:
As the result of advances in the understanding of molecular bases of cancer and introduction of targeted therapy, laboratory medicine currently plays an indispensable role in the management of cancer patients (1) . Traditionally, the measurement of tumor markers has been a topic of major interest for both medical oncology and clinical chemistry/laboratory medicine. With time the well-establishe...
PURPOSE To generate a comprehensive "Secretome" of proteins potentially found in the blood and derive a virtual Affymetrix array. To validate the utility of this database for the discovery of novel serum-based biomarkers using ovarian cancer transcriptomic data. EXPERIMENTAL DESIGN The secretome was constructed by aggregating the data from databases of known secreted proteins, transmembrane o...
Ovarian cancer has a poor prognosis. Most patients are diagnosed with ovarian cancer when the disease has reached an advanced stage and cure rates are generally under 30%. Hence, early diagnosis of ovarian cancer is the best means to control the disease in the long term and abate mortality. So far, cancer antigen 125 (CA125) and human epididymis protein 4 (HE4) are the gold-standard tumor marke...
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