A quartz crystal microbalance with dissipation monitoring (QCM-D) was used to study the adsorption of the layer formed by silica nanoparticles (SNP) and cellulose nanofibrils (NFC) together with cationic polyacrylamide (C-PAM) on cellulose surface, accompanied by use of atomic force microscope (AFM) to study the interactions between cellulose surfaces. The purpose was to understand the multilay...

A critical role for peptide C-terminal amidation was apparent when the first bioactive peptides were identified. The conversion of POMC into adrenocorticotropic hormone and then into α-melanocyte-stimulating hormone, an amidated peptide, provided a model system for identifying the amidating enzyme. Peptidylglycine α-amidating monooxygenase (PAM), the only enzyme that catalyzes this modification...

BACKGROUND Acute post-anoxic myoclonus (PAM) can be divided into an unfavorable (generalized/subcortical) and more favorable ((multi)focal/cortical) outcome group that could support prognostication in post-anoxic encephalopathy; however, the inter-rater variability of clinically assessing these PAM subtypes is unknown. METHODS We prospectively examined PAM patients using a standardized video ...

Pulmonary alveolar microlithiasis (PAM) is a rare, autosomal recessive lung disorder associated with progressive accumulation of calcium phosphate microliths. Inactivating mutations in SLC34A2, which encodes the NPT2b sodium-dependent phosphate cotransporter, has been proposed as a cause of PAM. We show that epithelial deletion of Npt2b in mice results in a progressive pulmonary process charact...

The energy efficiency of pulse-amplitude-modulated discrete multitone modulation (PAM-DMT) decreases as the modulation order of M-PAM modulation increases. Enhanced PAM-DMT (ePAM-DMT) was proposed as a solution to the reduced energy efficiency of PAM-DMT. This was achieved by allowing multiple streams of PAM-DMT to be superimposed and successively demodulated at the receiver side. In order to m...

A mutation in the IIb sodium phosphate transporter SLC34A2 gene has recently been described in pulmonary alveolar microlithiasis (PAM) patients. Experiments in this study were aimed at confirming the role of the gene product in PAM by comparing phosphorylated products in extracellular fluid of alveolar epithelial cells overexpressing the SLC34A2 gene or its mutated version. Eukaryotic expressio...

PURPOSE To our knowledge from indexed literature, the present study is the first one to systematically review the influence of local delivery of pamidronate (PAM) and/or ibandronate (IBA) on osseointegration enhancement. The aim of the present systematic review was to assess the efficacy of IBA and/or PAM local delivery (topically or coating on implants surfaces) in promoting osseointegration. ...

Streptococcus pyogenes Cas9 (SpCas9) is the most widely used genome editing tool in plants. The induced by SpCas9 strictly requires a canonical NGG protospacer-adjacent motif (PAM), significantly limiting its scope of application. Recently, five variants, SpCas9-NRRH, SpCas9-NRCH, SpCas9-NRTH, SpG, and SpRY, were developed to recognize non-canonical PAMs human cells. In this study, these varian...

The paper deals with the PAM manipulator modeling and identification based on autoregressive recurrent neural networks. For the first time, the most powerful types of neural-network-based nonlinear autoregressive models, namely, NNARMAX, NNOE and NNARX models, will be applied comparatively to the PAM manipulator identification. Furthermore, the evaluation of different nonlinear neural network a...

We present two SiP modulator architectures for PAM-4 signal generation. We demonstrate the transmission of 56 Gbaud PAM-4 over 1 km of SMF. An 84 Gbaud PAM-4 generation below KP4 FEC threshold is also achieved. OCIS codes: (130.0130); (230.2090); (230.4110);