BACKGROUND Insulin-like growth factor-1(IGF-1) has a multitude of effects besides cell growth and metabolism. Reports also indicate anti-inflammatory and antioxidative effects. The concentrations of IGF-1 decrease with age and during inflammation. As selenium and coenzyme Q10 are involved in both the antioxidative defense and the inflammatory response, the present study aimed to examine the eff...

Background: Acute renal injury (AKI) is one of the most common causes of mortality in children admitted to intensive care units (PICU). Here, we investigated the preventive effect of N-acetylcysteine ​​(NAC) and Coenzyme Q10 on AKI among children admitted to PICU. Methods: This double-blind randomized clinical trial study was done on 78 children admitted to PICU in 2018. Patients were randomly...

Nitrogen (N) fertilization has a considerable effect on food production and carbon cycling in agro-ecosystems. However, the impacts of N fertilization rates on the temperature sensitivity of soil respiration (Q10) were controversial. Five N rates (N0, N45, N90, N135, and N180) were applied to a continuous winter wheat (Triticum aestivum L.) crop on the semi-arid Loess Plateau, and the in situ s...

OBJECTIVE Evidence of oxidative stress was reported in individuals with Down syndrome. There is a growing interest in the contribution of the immune system in Down syndrome. The aim of this study is to evaluate the coenzyme Q10 and selected pro-inflammatory markers such as interleukin 6 and tumor necrosis factor α in children with Down syndrome. METHODS Eighty-six children (5-8 years of age) ...

The purpose of this study was to investigate the levels of coenzyme Q10 and vitamin E and the antioxidant status in subjects with metabolic syndrome (MS). Subjects with MS (n = 72) were included according to the criteria for MS. The non-MS group (n = 105) was comprised of healthy individuals with normal blood biochemical values. The plasma coenzyme Q10, vitamin E concentrations, lipid profiles,...

OBJECTIVE This study examined the effects of coenzyme Q10 administration on physical fatigue. METHODS In a double-blinded, placebo-controlled, three crossover design, 17 healthy volunteers were randomized to oral coenzyme Q10 (100 or 300 mg/d) or placebo administration for 8 d. As a fatigue-inducing physical task, subjects performed workload trials on a bicycle ergometer at fixed workloads tw...

The objective was to assess the efficacy of coenzyme Q10 as a preventive treatment for migraine headaches. Thirty-two patients (26 women, 6 men) with a history of episodic migraine with or without aura were treated with coenzyme Q10 at a dose of 150 mg per day. Thirty-one of 32 patients completed the study; 61.3% of patients had a greater than 50% reduction in number of days with migraine heada...

[1] The production of CO2 by soil microorganisms is an important component of the global carbon cycle, and its temperature sensitivity is poorly constrained in global models. To improve our understanding of the factors controlling the temperature dependence of soil microbial respiration, we analyzed the temperature sensitivity of labile soil organic carbon decomposition for 77 soils collected f...