http://dx.doi.org/10.1016/j.displa.2014.11.003 0141-9382/ 2014 Elsevier B.V. All rights reserved. ⇑ Corresponding author at: Institut des Sciences du Mouvement, UMR CNRS 7287, Aix-Marseille Université, 163 avenue de Luminy, 13009 Marseille, France. Tel.: +33 491 17 04 55. E-mail address: [email protected] (R.J. Bootsma). Olivier Borg , Remy Casanova , Camille Coton , Charlie Barla , R...

For a left-compressed intersecting family A ⊆ [n] and a set X ⊆ [n], let A(X) = {A ∈ A : A ∩ X 6= ∅}. Borg asked: for which X is |A(X)| maximised by taking A to be all r-sets containing the element 1? We determine exactly which X have this property, for n sufficiently large depending on r.

STUDY OBJECTIVES We have previously shown that tiotropium at 18 mug reduces lung hyperinflation and dyspnea during exercise and improves exercise tolerance in patients with COPD. The present study was designed to gain further insight into the duration of improvements. DESIGN, PATIENTS, AND INTERVENTIONS A randomized, double-blind, placebo-controlled, parallel-group study was conducted in 261 ...

BACKGROUND Few data are available about the effects of respiratory muscle training with normocapnic hyperpnea (NH) in COPD. The aim is to evaluate the effects of 4 weeks of NH (Spirotiger(®)) on ventilatory pattern, exercise capacity, and quality of life (QoL) in COPD patients. METHODS Twenty-six COPD patients (three females), ages 49-82 years, were included in this study. Spirometry and maxi...

In epidemiological studies, defining asthma as the presence of airway hyperresponsiveness (AHR) plus recent symptoms leaves two groups of subjects whose clinical significance is unclear: those with asymptomatic AHR, and those with symptoms only. The aim of the study was to determine whether subjects with symptoms only differ from the normal and asthmatic groups in the perception of airway obstr...

Whether exertional dyspnoea can be attributed to poor circulatory-muscular conditioning is a difficult clinical issue. Because criteria of poor conditioning such as low oxygen pulse, low ventilatory threshold or high heart rate/oxygen consumption slope can be observed in heart or lung diseases and are not specific to conditioning, we assessed the relationships between physical exercise, conditi...

OBJECTIVES This study was designed (a) to evaluate an improved quantitative lung fibrosis score based on a computer-aided diagnosis (CaM) system in patients with systemic sclerosis (SSc),-related interstitial lung disease (SSc-ILD), (b) to investigate the relationship between physiologic parameters (forced vital capacity [FVC] and single-breath diffusing capacity for carbon monoxide [DLCO]), pa...

Objectives: Although noninvasive ventilation has shown promise in acute obstructive lung disease, use of continuous positive airway pressure (CPAP) in pediatric asthma has not been examined prospectively. This study assessed the efficacy of CPAP in acute pediatric asthma exacerbations. Methods: Prospective, randomized, controlled trial at an urban emergency department (ED). A convenience sample...

Thomas Hamelryck, John Haslett, Kanti Mardia, John T. Kent, Jan Valentin, Jes Frellsen, Jesper Ferkinghoff-Borg The Bioinformatics center, University of Copenhagen, Denmark School of Computer Science and Statistics,Trinity College, Dublin Department of Statistics, School of Mathematics, The University of Leeds, UK Center for Biological Sequence Analysis, Technical University of Denmark, Lyngby,...