INTRODUCTION Ejaculation is a complex reflex mediated by a spinal ejaculation generator located in the lumbosacral spinal cord and consisting of a population of lumbar spinothalamic (LSt) neurons. LSt neurons and their intraspinal axonal projections contain several neuropeptides, including gastrin-releasing peptide (GRP). AIM To test the hypothesis that GRP is critically involved in mediating...

BACKGROUND Stent thrombosis (ST) after sirolimus-eluting stent implantation has not yet been adequately characterized, mainly because of its low incidence. METHODS AND RESULTS The Registry of Stent Thrombosis for Review and Reevaluation (RESTART) is a Japanese nationwide registry of sirolimus-eluting stent-associated ST comprising 611 patients with definite ST (early [within 30 days; EST], 32...

The downscaling of frequently-acquired geostationary Land Surface Temperature (LST) data can compensate the lack of high spatiotemporal LST data for urban climate studies. In order to be usable, the generated datasets must accurately reproduce the spatiotemporal features of the coarse-scale LST time series with greater spatial detail. This work concerns this issue and exploits the high temporal...

Several randomized and observational studies have reported steady increase in cumulative incidence of late and very late ST (LST/VLST) following first-generation drug-eluting stents (DES: sirolimus-(SES) and paclitaxel-(PES)) up to 5 years. Pathologic studies have identified uncovered struts as the primary substrate responsible for LST/VLST following DES, where delayed arterial healing is assoc...

Land Surface Temperature (LST) is one of the key parameters in the physics of land-surface processes on regional and global scales, combining the results of all surface-atmosphere interactions and energy fluxes between the surface and the atmosphere. With the advent of the European Space Agency (ESA) Sentinel 3 (S3) satellite, accurate LST retrieval methodologies are being developed by exploiti...

The development of an anti-bacterial drug in the form of a monoclonal antibody (mAb) targeting an exposed virulence factor, represents an innovative therapeutic strategy. Consequently, a fully human IgG1 mAb (LST-007) targeting Pseudomonas aeruginosa (PA) flagellin type b was recombinantly expressed and characterized in vitro and in an infection model driven by a multidrug resistant (MDR) PA st...

BACKGROUND Thiazolidinediones exert anti-inflammatory and anti-oxidative roles and attenuate atherosclerosis by mechanisms partially independent of their metabolizing actions. High doses of angiotensin type 1 receptor (AT1R) blocker losartan (LST) seem to promote fat cell formation by preserving PPARgamma activity. METHODS C57BL/6J diet-induced atherosclerotic susceptible mice randomly receiv...

This paper compares the normalized difference vegetation index (NDVI) and percent impervious surface as indicators of surface urban heat island effects in Landsat imagery by investigating the relationships between the land surface temperature (LST), percent impervious surface area (%ISA), and the NDVI. Landsat Thematic Mapper (TM) and Enhanced Thematic Mapper Plus (ETM+) data were used to estim...

[1] Comparison of the land surface skin temperature (LST) from the National Centers for Environmental Prediction (NCEP) operational Global Forecast System (GFS) against satellite and in situ data in summer 2007 indicates that the GFS has a large and cold bias in LST over the arid western continental United States (CONUS) during daytime. This LST bias contributes to large errors in simulated sat...

A single channel land surface temperature (LST) retrieval algorithm named Single Channel Water Vapor Dependent (SCWVD) method was presented for Medium Resolution Spectral Imager (MERSI) thermal infrared band aboard FengYun-3A (FY-3A) satellite. Water Vapor Content (WVC) is the only input parameter in the algorithm assuming the surface emissivity is known. NCEP reanalysis monthly mean datasets a...