The plasticity of cell-cell adhesive structures is crucial to all normal and pathological morphogenetic processes. The molecular principles of this plasticity remain unknown. Here we study the roles of two dimerization interfaces, the so-called strand-swap and X dimer interfaces of E-cadherin, in the dynamic remodeling of adherens junctions using photoactivation, calcium switch, and coimmunopre...

We consider the problem of accurately estimating a high-dimensional sparse vector using a small number of linear measurements that are contaminated by noise. It is well known that standard computationally tractable sparse recovery algorithms, such as the Lasso, OMP, and their various extensions, perform poorly when the measurement matrix contains highly correlated columns. We develop a simple g...

In this paper a new credit risk model for credit derivatives is presented. The model is based upon the ‘Libor market’ modelling framework for default-free interest rates. We model effective default-free forward rates and effective forward credit spreads as lognormal diffusion processes, and recovery is modelled as a fraction of the par value of the defaulted claim. The newly introduced survival...

OBJECTIVE Research has raised questions about the ability of clinicians to make reliable diagnostic judgments about personality. The aim of this study was to assess the reliability and validity of the dimensional diagnosis of pathological personality traits with the Shedler-Westen Assessment Procedure-200 (SWAP-200) Q sort. METHOD Two clinician/judges independently described 24 outpatients us...

purpose : to evaluate the efficacy of pattern visual evoked potentials (pvep), standard automated perimetry (sap), short-wavelength automated perimetry (swap), contrast sensitivity (cs), stereoacuity testing in detecting subclinical visual impairment in visually asymptomatic patients with multiple sclerosis (ms) and no history of optic neuritis methods : twenty-seven eyes of 27 patients (7 male...

PURPOSE To determine the magnitude of the homogeneous, LF(Ho), and the heterogeneous, LF(He), components of the long-term fluctuation (LF) in glaucoma suspects and in stable primary open angle glaucoma (POAG) patients undergoing short-wavelength automated perimetry (SWAP) and to compare the magnitude of the SWAP LF components with those elicited by standard white-on-white (W-W) perimetry. MET...

PURPOSE To compare the performance of standard automated perimetry (SAP), frequency-doubling technology (FDT) perimetry, and short-wavelength automated perimetry (SWAP) in detecting glaucoma. METHODS One hundred thirty-two eyes of 95 glaucoma patients and 37 normal subjects had retinal nerve fiber layer (RNFL) imaging and visual field testing by SAP, Matrix FDT perimetry, and Swedish interact...

PURPOSE To compare the Swedish interactive thresholding algorithm (SITA) with the full-threshold (FT) strategy for short-wavelength automated perimetry (SWAP). METHODS One eye of 286 patients with glaucomatous optic neuropathy (GON) and 289 age-matched participants without GON from the Diagnostic Innovations in Glaucoma Study (DIGS) and the African Descent and Glaucoma Evaluation Study (ADAGE...

Detection of progression is paramount to the clinical management of glaucoma. Our goal is to compare the performance of standard automated perimetry (SAP), short-wavelength automated perimetry (SWAP), and frequency-doubling technology (FDT) perimetry in monitoring glaucoma progression.Longitudinal data of paired SAP, SWAP, and FDT from 113 eyes with primary open-angle glaucoma enrolled in the D...

BACKGROUND The purpose of this study was to evaluate short-wavelength automated perimetry (SWAP, i.e., blue-yellow) in normal volunteers and to review the current normal values provided by the manufacturer. METHODS 28 eyes of 28 normal subjects (age range 21-48 years, mean age 36.5 years) had SWAP (Octopus 101, two phases of program G2, Interzeag AG, Schlieren, Switzerland). All subjects had ...