Offline power converter products must apply for and pass the national electrical safety code before they can be marketed. The transformers of offline converters made from certificated materials with a high voltage rating insulation, which increases volume printed circuit boards. In most studies, miniaturization is usually achieved by increasing conversion efficiency reducing heat sink, or switc...

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Lyotropic liquid crystalline (LLC) phases from helical β-peptides are proposed as novel water-based alignment media. In contrast to α-peptides, β-peptides form LLCs at very short chain lengths and at concentrations as low as 1 percent. Spectra obtained in these LLC phases are artefact-free and lead to RDCs of the desired size. First indications towards enantiodiscrimination are provided.

www.panstanford.com Raj Bawa, MS, PhD,a S. R. Bawa, MSc, PhD,b and Ratnesh N. Mehra, DOc aBawa Biotech LLC, Ashburn, Virgina, USA and Department of Biological Sciences, Rensselaer Polytechnic Institute, Troy, New York, USA bBawa Biotech LLC, Schenectady, New York, USA cDepartment of Neurosurgery, Michigan State University College of Osteopathic Medicine, St. John Providence Health System, Michi...

BACKGROUND Shikonin derivatives have cytotoxic and antitumor effects. This study aims to investigate the antitumor effects of acetylshikonin isolated from a Chinese medicinal herb Arnebia euchroma (Royle) Johnst. METHODS The 3-(4,5-dimethylthiazol- 2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was used to determine the in vitro antitumor effects of acetylshikonin on human lung adenocarcin...

Several signaling pathways that regulate tight junction and adherens junction assembly are being characterized. Calpeptin activates stress fiber assembly in fibroblasts by inhibiting SH2-containing phosphatase-2 (SHP-2), thereby activating Rho-GTPase signaling. Here, we have examined the effects of calpeptin on stress fiber and junctional complex assembly in Madin-Darby canine kidney (MDCK) and...

L-Histidine and imidazole (the histidine side chain) significantly increase cAMP accumulation in intact LLC-PK1 cells. This effect is completely inhibited by isobutylmethylxanthine (IBMX). Histidine and imidazole stimulate cAMP phosphodiesterase activity in soluble and membrane fractions of LLC-PK1 cells suggesting that the IBMX-sensitive effect of these agents to stimulate cAMP formation is no...

OBJECTIVES The objective of this study was an investigation of the safety and efficacy of primary below-knee stent-supported angioplasty (BKSSA) for restoring straight inline arterial flow in patients with critical limb ischemia (CLI) or lifestyle-limiting claudication (LLC). BACKGROUND Surgical tibial bypass for CLI and severe LLC is associated with significant morbidity, mortality, and graf...