نتایج جستجو برای: ظرفیت برد فیزیکی pcc

تعداد نتایج: 62456  

2015
Rozenn Jossé Yong-Wei Zhang Valentin Giroux Arun K. Ghosh Ji Luo Yves Pommier Angela Capper

Lasonolide A (LSA), a potent antitumor polyketide from the marine sponge, Forcepia sp., induces rapid and reversible protein hyperphosphorylation and premature chromosome condensation (PCC) at nanomolar concentrations independent of cyclin-dependent kinases. To identify cellular targets of LSA, we screened 2951 shRNAs targeting a pool of human kinases and phosphatases (1140 RefSeqs) to identify...

2015
Adrian R Parry-Jones Mario Di Napoli Joshua N Goldstein Floris H B M Schreuder Sami Tetri Turgut Tatlisumak Bernard Yan Koen M van Nieuwenhuizen Nelly Dequatre-Ponchelle Matthew Lee-Archer Solveig Horstmann Duncan Wilson Fulvio Pomero Luca Masotti Christine Lerpiniere Daniel Agustin Godoy Abigail S Cohen Rik Houben Rustam Al-Shahi Salman Paolo Pennati Luigi Fenoglio David Werring Roland Veltkamp Edith Wood Helen M Dewey Charlotte Cordonnier Catharina J M Klijn Fabrizio Meligeni Stephen M Davis Juha Huhtakangas Julie Staals Jonathan Rosand Atte Meretoja

OBJECTIVE There is little evidence to guide treatment strategies for intracerebral hemorrhage on vitamin K antagonists (VKA-ICH). Treatments utilized in clinical practice include fresh frozen plasma (FFP) and prothrombin complex concentrate (PCC). Our aim was to compare case fatality with different reversal strategies. METHODS We pooled individual ICH patient data from 16 stroke registries in...

Journal: :Lancet 2015
Joshua N Goldstein Majed A Refaai Truman J Milling Brandon Lewis Robert Goldberg-Alberts Bruce A Hug Ravi Sarode

BACKGROUND Rapid reversal of vitamin K antagonist (VKA)-induced anticoagulation is often necessary for patients needing urgent surgical or invasive procedures. The optimum means of VKA reversal has not been established in comparative clinical trials. We compared the efficacy and safety of four-factor prothrombin complex concentrate (4F-PCC) with that of plasma in VKA-treated patients needing ur...

2015
Xiaofang You Hui Tan Shiyun Hu Jianmei Wu Hong Jiang Aiping Peng Yue Dai Ling Wang Sufang Guo Xu Qian

BACKGROUND Migrants have long been a disadvantaged group in China's health care system, especially in terms of maternal health care. Many studies have explored the factors associated with a lack of maternal health care and found many determinants, including social, economic, behavioral, and environmental factors. However, studies focusing on factors associated with maternal health care have rar...

Journal: :Turkish journal of medical sciences 2014
Benan Bayrakci Selman Kesici Tanıl Kendirli Gökhan Kalkan Aydın Sari Necvan Tokmak Gökmen Yilmaz Orkun Baloğlu İrfan Şencan

BACKGROUND/AIM To collect data from throughout Turkey in order to facilitate the organization of pediatric intensive care units (PICUs), and to develop short-term immediate action plans and draft long-term strategic plans. MATERIALS AND METHODS A total of 35 specialists including 17 pediatric critical care (PCC) specialists, 9 PCC fellows in training, and 9 pediatricians working in PICUs eval...

2012
Esther Korpershoek Karel Pacak Lucia Martiniova

Pheochromocytomas (PCCs) are slow-growing neuroendocrine tumors arising from adrenal chromaffin cells. Tumors arising from extra-adrenal chromaffin cells are called paragangliomas. Metastases can occur up to approximately 60% or even more in specific subgroups of patients. There are still no well-established and clinically accepted "metastatic" markers available to determine whether a primary t...

Journal: :BJA: British Journal of Anaesthesia 2009
G. Dickneite I. Pragst

BACKGROUND Fluid resuscitation following traumatic injury causes haemodilution and can contribute to coagulopathy. Coagulation factor replacement may be necessary to prevent bleeding complications of dilutional coagulopathy. Compared with fresh frozen plasma (FFP), prothrombin complex concentrate (PCC) may potentially offer a more rapid and effective means of normalizing coagulation factor leve...

Journal: :Stem cells 1995
W F Blakely P G Prasanna C J Kolanko M D Pyle D M Mosbrook A S Loats T L Rippeon H Loats

The premature chromosome condensation (PCC) assay has been proposed as a useful and rapid end point for biological dosimetry following accidental high-dose radiation overexposures. A major benefit of the PCC assay is that it does not require cells to divide for evaluation of cytogenetic damage. The PCC assay was performed on isolated human peripheral lymphocytes exposed in vitro to doses from 1...

2017
Dong Wang Li Song Liang Wang Lianmei Zhao Bai Xiang Ying Li Baoen Shan Jing Liu

Pheochromocytoma (PCC) is related to germline mutations in 12 susceptibility genes. Although comparative genomic hybridization array has revealed some putative tumor suppressor genes on the short arm of chromosome 1 that are likely to be involved in PCC tumorigenesis, the molecules involved, except for those encoded by known susceptibility genes, have not been found in the generation of sporadi...

2016
Christian J. Wiedermann Giovanni Mariscalco Daniele Maselli Aamer B. Ahmed Fausto Biancari

In a retrospective study of bleeding patients in cardiac surgery, Cappabianca et al. [1] observed that the use of prothrombin complex concentrate (PCC) compared with fresh-frozen plasma (FFP) was associated with a higher risk of postoperative renal complications. In the unadjusted comparison, acute kidney injury (AKI) incidence was significantly higher in the PCC group, and use of PCC was an in...

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