The inflammatory disease human T cell lymphotropic virus type I (HTLV-I)-associated myelopathy (HAM/TSP) occurs in only 1-2% of HTLV-I-infected individuals and is associated with a high provirus load of HTLV-I. We hypothesize that a person's risk of developing HAM/TSP depends upon the efficiency of their immune response to the virus, which differs between individuals because of polymorphism in ...

Human T cell lymphotropic virus type 1 (HTLV-1) infection can lead to development of adult T cell leukemia/lymphoma (ATL) or HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in a subset of infected subjects. Understanding the interaction between host and HTLV-1 and the molecular mechanisms associated with disease pathogenesis is critical for development efficient therapies. T...

Although some recent studies concluded that dexterity is not a reliable predictor of performance in preclinical laboratory courses in dentistry, they could not disprove earlier findings which confirmed the worth of manual dexterity tests in dental admission. We developed a wire bending test (HAM-Man) which was administered during dental freshmen's first week in 2008, 2009, and 2010. The purpose...

Human T-lymphotropic virus type 1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a rare neurodegenerative disease characterized by chronic inflammation in the spinal cord. We hypothesized that a positive feedback loop driven by chemokines may be responsible for the chronic inflammation in HAM/TSP. We aimed to determine the identity of these chemokines, where they are produced, ...

Human T lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is an inflammatory neurologic disease caused by HTLV-I infection and has been associated with elevated levels of several proinflammatory cytokines in both serum and cerebrospinal fluid. It is unknown what kind of cells secrete these cytokines and if HTLV-I Ags are associated with this phenome...

Processed and red meat consumption is associated with the risk of colorectal cancer. Meta-analyses have suggested that the risk associated with processed meat is higher. Most processed meats are cured and cooked, which leads to formation of free nitrosyl heme. We speculated that free nitrosyl heme is more toxic than native myoglobin. The promoting effect of a freeze-dried, cooked, cured ham die...

In this paper, the convergence of Zakharov-Kuznetsov (ZK) equation by homotopy analysis method (HAM) is investigated. A theorem is proved to guarantee the convergence of HAM and to nd the series solution of this equation via a reliable algorithm.

Homotopy Analysis Method (HAM) is applied to find the critical buckling load of the Euler columns with continuous elastic restraints. HAM has been successfully applied to many linear and nonlinear, ordinary and partial, differential equations, integral equations, and difference equations. In this study, we presented the application of HAM to the critical buckling loads for Euler columns with fi...

This paper presents the application of the Homotopy Analysis Method (HAM) as a numerical solution to linear integro-differential equation. The HAM contains the auxiliary parameter , taht provides a powerful tool to analyze strongly linear and nonlinear problems. Examples are provided to demonstrate the advantages of HAM over the homotopy perturbation method (HPM), sine-cosine wavelets and CAS w...