In the present study a unique antibody (NKI-L16) reacting with the alpha-chain of the human leukocyte function-associated Ag-1 (LFA-1) is described, which stimulates homotypic cell-cell interactions in a manner very similar to 12-O-tetradecanoyl-phorbol-13-acetate (TPA), in contrast to other anti-LFA-1 mAb which inhibit cell aggregation. The induction of aggregate formation of EBV-transformed B...

The location of ribosomal protein L7/L12 has been examined by fluorescence spectroscopy. Protein L7 modified mainly at the COOH terminus by 5-(iodoacetamidoethyl)-aminonaphthalene-1-sulfonic acid, and yeast tRNAPhe-containing fluorescent dyes located specifically near the anticodon or at the 3'-end were used in these studies. Fluorescence-quenching measurements indicate that the COOH terminus o...

Migration is a bigger option for earning and livelihood in Odisha either push factors or pull factors, which people move to other states search of work better wages. But COVID-19 emerged as crippling blow huge reverse migration being noticed the state. So study tried investigate labour supply employment opportunity rural areas due COVID-19-led examine impact on status, income profile returned m...

Trypanosoma cruzi infection of host cells is a complex process in which many proteins participate but only a few of these proteins have been identified experimentally. One parasite factor likely to be involved is the protein product of LYT1, a single-copy gene cloned, sequenced, and characterized by Manning-Cela et al. (Infect. Immun. 69:3916-3923, 2001). This gene was potentially associated wi...

Incubation of 50 S subunits from Escherichia coli in the presence of 1.5 M LiCl yielded 1 . 5 ~ core particles which contained -20 proteins and were inactive with respect to peptidyltransferase activity. The proteins of the split fraction were isolated and their effects with respect to restoration of activity were tested in reconstitution assays. Purified L16 was able to restore activity, but t...

Identification of all the protein components of the large subunit (39 S) of the mammalian mitochondrial ribosome has been achieved by carrying out proteolytic digestions of whole 39 S subunits followed by analysis of the resultant peptides by liquid chromatography and mass spectrometry. Peptide sequence information was used to search the human EST data bases and complete coding sequences were a...