The 46th Annual Meeting of the American Society of Clinical Oncology, held in Chicago, included topics covering new therapeutic developments in the field of oncology. This conference report highlights selected presentations on novel therapies for cancers including glioblastoma, breast cancer, myeloma, NSCLC and solid tumors. Investigational drugs discussed include rindopepimut and PF-299804 (bo...

هدف: هدف از این پژوهش بررسی واسطه‌­ای راهبردهای سازش نایافته تنظیم شناختی هیجان در رابطه باورهای فراشناختی با اضطراب امتحان بود. روش: روش حاضر توصیفی و نوع همبستگی جامعه آماری را کلیه دانش‌­آموزان پسر دوره دوم متوسطه شهر تهران سال تحصیلی 1401-1400 تشکیل دادند که تعداد 456 نفر به نمونه‏‌گیری دسترس انتخاب شرکت کردند. ابزارها شامل سیاهه ابوالقاسمی همکاران (1375)، پرسشنامه باکو دیگران (2009)، فرم ک...

امروزه مدیریت زنجیره تأمین باید راهکارهایی را اتخاذ کند تا بتواند پاسخگوی نیازهای متغیر مشتریان باشد. استفاده از هوشمندی کسب­وکار به­همراه تقویت یکپارچگی و قابلیت چابکی، موجب ایجاد مزیت رقابتی در می­شود درنتیجه می­تواند موقعیت بهتری کسب­‌وکار داشته هدف این پژوهش، بررسی چگونگی تأثیر کسب‌­وکار بر یکپارچگی، چابکی عملکرد است. درضمن اثر موردبررسی قرار می­‌گیرد. پژووهش ابتدا با مرور پیشینه موضوع، یک ...

This international symposium dealt with ion channels in pain and neuroprotection. It consisted of five sessions, each with four to five presentations, three plenary lectures, and 50 posters. It was sponsored and organized by Roche Bioscience with additional support from Astra, Pfizer, Abbot, RBI, Merck, Novartis, Rhone-Poulenc and Wyeth. Approximately 400 academic and industrial scientists atte...

1 Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam, 2 Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom, 3 Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam, 4 Hoffmann-La Roche, Nutley, New Jersey, United States of America, 5 Novartis Institute for Tropical Diseases, Biopolis Wa...

Employment or Leadership: N.G. Morgenthaler, BRAHMS; A. Bergmann, BRAHMS. Consultant or Advisory Role: M.H. Brutsche, advisory boards for Pfizer (Champix, Spiriva), GlaxoSmithKline, and Novartis; C. Mueller, BRAHMS and Abbott Laboratories. Stock Ownership: A. Bergmann, BRAHMS. Honoraria: C. Mueller, Biosite, Abbott Laboratories, Roche, BRAHMS, and Siemens. Research Funding: M.T. Maeder, Swiss S...

Affiliations: 6 Gladstone Institute of Virology and Immunology, San Francisco CA 94158, USA 7 Department of Medicine, University of California, San Francisco, San Francisco CA 94158, 8 USA 9 Current Address: Novartis Institutes for Biomedical Research (NIBR), Inc., Cambridge, MA 02139, 10 USA 11 Buck Institute for Research on Aging, Novato, CA 94945, USA 12 *These authors contributed equally 13...

Response at 60-Months of Age in Children Who Received Infant Or Toddler Doses of MenACWY-CRM Conjugate Vaccine Nicola P. Klein, MD, PhD; Stan L. Block, MD; William Johnston, MD; Sandra Percell, PhD; Linda Han, MD; Peter M Dull, MD; Igor Smolenov, MD; Kaiser Permanente Vaccine Study Center, Oakland, CA; Kentucky Pediatric Research Center, Bardstown, KY; Alabama Clinical Therapeutics, Birmingham,...

This decline can be attributed primarily to a more cautious regulatory climate caused by recent highprofile safety issues. 3 As a result of the heightened bar to obtain FDA approval, the life sciences sector has been plagued by a dearth of new product flow. All players in the industry—even large pharmaceutical companies—have been affected. Notably, only Novartis and GlaxoSmithKline (GSK) releas...

The workshop chair, Eric Cornut, President of the pharmaceutical manufacturer Novartis (France), which produces, among other things, anti-malarial medicines derived from artemisinin, reminded us of the scourge that so many infectious and parasitic diseases still represent in our today, especially in the countries of the South. While calling for increased international efforts to combat communic...