BACKGROUND Changes in choroidal circulation hemodynamics during the course of punctate inner choroidopathy (PIC) remain unknown. The aim of this study was to quantitatively evaluate changes in choroidal blood flow velocity by using laser speckle flowgraphy (LSFG) in patients with PIC. CASE PRESENTATION This PIC patient was initially treated with systemic corticosteroids for 4 months. LSFG mea...

OBJECTIVES To characterise the clinical features, emergency pre-paediatric intensive care (PIC) treatment, and course of status epilepticus (SE) in children admitted to PIC. This may provide insight into reasons for admission to PIC and provide a framework for the development of strategies that decrease the requirement for intensive care. DESIGN Cross sectional, retrospective study. SETTING...

Chromium picolinate [Cr(pic)(3)] is a nutritional supplement widely promoted to exert beneficial metabolic effects in patients with type 2 diabetes/impaired glucose tolerance. Frequent comorbidities in these individuals include systemic hypertension, abnormal vascular function and ischemic heart disease, but information on the effects of the supplement on these aspects is sparse. Utilizing male...

PURPOSE This study sought to identify and characterize subtypes of alpha 2-adrenoceptors in rabbit ciliary body. METHODS Radioligand binding assays were performed with the alpha 2-agonist ligand [125I]-p-iodoclonidine ([125I]PIC) and the antagonist ligand [3H]rauwolscine. RESULTS Both [125I]PIC and [3H]rauwolscine bound to a single population of receptors in membrane preparations of rabbit ...

This paper presents a personal computer (PC)-based data acquisition and control tool that uses a Peripheral Interface Controller (PIC) microcontroller, Matlab, and Simulink. Specifically, a library of PIC microcontroller functions for Simulink is created. Moreover, the PIC microcontroller and Matlab are merged, by exploiting their serial communication capability, to produce an inexpensive data ...

With the advance of mature fabrication technologies, photonic integrated circuits (PICs) reach ever-higher levels of complexity. Integration of thousands of components has been shown [1], with each main technology showing an exponential growth in complexity [2]. This increase in complexity requires a convergence in technologies, and the roadmaps are currently being pushed by silicon nitride, (h...

A new species of the fire-colored beetle genus Pseudopyrochroa Pic, 1906, is described from the Mae Chaem District, Chiang Mai Province, Thailand. The new species, Pseudopyrochroa inthanonensis sp. nov., is superficially similar to Pseudopyrochroa basalis (Pic), Pseudopyrochroa cardoni (Fairmaire) and Pseudopyrochroa fainanensis (Pic) by virtue of body color, antennal form and prothoracic shape...

A complete, 52-protein, 2.5 million dalton, Mediator-RNA polymerase II pre-initiation complex (Med-PIC) was assembled and analyzed by cryo-electron microscopy and by chemical cross-linking and mass spectrometry. The resulting complete Med-PIC structure reveals two components of functional significance, absent from previous structures, a protein kinase complex and the Mediator-activator interact...

In the months after spinal cord transection, motoneurons in the rat spinal cord develop large persistent inward currents (PICs) that are responsible for muscle spasticity. These PICs are mediated by low-threshold TTX-sensitive sodium currents (Na PIC) and L-type calcium currents (Ca PIC). Recently, the Na PIC was shown to become supersensitive to serotonin (5-HT) after chronic injury. In the pr...