There has been increasing recognition that antipsychotic nonadherence is common across all stages of schizophrenia, starting from the first episode. Moreover, numerous meta-analyses of the existing literature indicate superiority of long-acting injectable (LAI) over oral antipsychotics when one adjusts for the greater illness severity and duration among patients in LAI antipsychotic trials. The...

BACKGROUND Antipsychotic medications are a central component of effective treatment for schizophrenia, but nonadherence is a significant problem for the majority of patients. Long-acting injectable (LAI) antipsychotic medications are a recommended treatment option for nonadherent patients, but evidence regarding their potential advantages has been mixed. Observational data on newer, second-gene...

Leaf area index (LAI), the total one-sided surface area of leaf per ground surface area, is a key component of land surfacemodels. The authors investigate the influence of differing, plausible LAI prescriptions on heat, moisture, and carbon fluxes simulated by the Community Atmosphere Biosphere Land Exchange version 1.4b (CABLEv1.4b) model over the Australian continent. A 15-member ensemble mon...

The Leaf Area Index (LAI) is a key variable in many land surface and climate modeling studies. To date, a number of LAI datasets have been developed based on time series of medium resolution optical remote sensing observations. Global validation exercises show the high value of these datasets, but at the same time they point out shortcomings, particularly in the presence of persistent cloud cov...

Bamboo forests, especially the Moso bamboo forest (MBF) and the Lei bamboo forest (LBF), have a strong carbon sequestration capability and play an important role in the global forest carbon cycle. The leaf area index (LAI) is an important structural parameter for simulating the spatiotemporal pattern of the carbon cycle in bamboo forests. However, current LAI products suffer from substantial no...

BACKGROUND French clinical recommendations suggest prescribing long-acting injectable (LAI) antipsychotics to patients with a maintenance treatment indication in schizophrenia. Despite this, and due to their relatively high acquisition and administration costs, LAIs are still underused in clinical practice in France, thus highlighting the need for pharmacoeconomic evaluations. OBJECTIVE Our o...