OBJECTIVE To determine whether transthoracic three dimensional echocardiography is an accurate non-invasive technique for defining the morphology of atrial septal defects (ASD). METHODS In 34 patients with secundum ASD, mean (SD) age 20 (17) years (14 male, 20 female), the measurements obtained from three dimensional echocardiography were compared to those obtained from magnetic resonance ima...

Gridpoint statistical interpolation (GSI), a three-dimensional variational data assimilation method (3DVAR) has been widely used in operations and research in numerical weather prediction. The operational GSI uses a static background error covariance, which does not reflect the flow-dependent error statistics. Incorporating ensemble covariance in GSI provides a natural way to estimate the backg...

We examine security protocols for the Grid Security Infrastructure (GSI) version 2 and identify a weakness of poor scalability as a result of GSI’s authentication framework requiring heavy interactions between a user-side client machine and resource suppliers. We improve the GSI architecture and protocols by proposing an alternative authentication framework for GSI, which uses dynamic public/pr...

The Geological Strength Index (GSI) system, proposed in 1995, is now widely used for the estimation of the rock mass strength and the rock mass deformation parameters. The GSI system concentrates on the description of two factors, rock structure and block surface conditions. The guidelines given by the GSI system are for the estimation of the peak strength parameters of jointed rock masses. The...

BACKGROUND The aim of this study was to investigate the urodynamic parameters and lower urinary tract symptoms (LUTS) of women with urodynamic genuine stress incontinence (GSI). METHODS A cross-sectional study involving 3323 women with LUTS was conducted. We recruited 1261 women with urodynamic GSI and were further grouped as with or without symptomatic stress urinary incontinence (SUI). The ...

The T-cell lymphoproliferative neoplasms (T-LPN) are characterized by a poor clinical outcome. Current therapeutics are mostly non-selective and may induce harmful side effects. It has been reported that NOTCH1 activation mutations frequently associate T-LPN. Because anti-Notch1 based therapies such as γ-secretase inhibitors (GSI) are less efficient and induce considerable side effects, we hypo...