Neven Sesardic has recently defended his arguments in favour of racial naturalism-the view that race is a valid biological category-in response to my criticism of his work. While Sesardic claims that a strong version of racial naturalism can survive critique, he has in fact weakened his position considerably. He concedes that conventional racial taxonomy is arbitrary and he no longer identifies...

Background: Epidemiologic, clinical, and experimental studies have suggested that fish oil (FO), a rich source of n-3 (ω-3) polyunsaturated fatty acids, protects against colon cancer. However, this message is confounded by the FDA's warning that the consumption of certain types of fish should be restricted because of contamination with persistent organic pollutants (POPs), such as polychlorinat...

We have mutagenized a clinical strain of Salmonella enterica sv. typhi with mini-transposon Tn10dTet (T-POP) to obtain conditional lethal (tetracycline-dependent) mutants with T-POP insertions upstream of essential genes. Generalized transducing phage P22 was used to introduce T-POP from a S. typhimurium donor into a S. typhi recipient. Chromosomal DNA was purified from the mutagenized donor st...

Background. Application of new tools for epidemiological investigations, such as Geographical Information Systems (GIS), offers a new approach and possibilities for the eradication or control of infectious diseases. For this reason we developed epidemiological GIS-based maps for meningitis due to Haemophilus influenzae typo b (Hib), Streptococcus pneumoniae (Sp), Neisseria meningitidis (Nm) and...

We carried out a national survey on postoperative pain (POP) management in a representative sample (public/private, teaching/non-teaching, size) of 76 surgical centers in France. Based on medical records and questionnaires, we evaluated adult patients 24h after surgery, concerning information: pre and postoperative pain, evaluation, treatment and side effects. A local consultant provided inform...

Hypothesis / aims of study Pelvic Organ Prolapse (POP) and Stress Urinary Incontinence (SUI) are multifactorial diseases that negatively affect the quality of life of millions of women. The pathophysiology of these diseases is not fully elucidated. All previously examined tissue specimens from women with POP were examined with techniques that measured differences of expression of specific prote...

Drag-and-pop and drag-and-pick are interaction techniques designed for users of penand touchoperated display systems. They provide users with access to screen content that would otherwise be impossible or hard to reach, e.g., because it is located behind a bezel or far away from the user. Drag-and-pop is an extension of traditional drag-and-drop. As the user starts dragging an icon towards some...

To form the proximal-distal axis of the C. elegans gonad, two somatic gonadal precursor cells, Z1 and Z4, divide asymmetrically to generate one daughter with a proximal fate and one with a distal fate. Genes governing this process include the lin-17 frizzled receptor, wrm-1/beta-catenin, the pop-1/TCF transcription factor, lit-1/nemo-like kinase, and the sys-1 gene. Normally, all of these regul...

Prolyl oligopeptidase (POP), a member of the prolyl endopeptidase family, is known to play a role in several neurological disorders. Its primary function is to cleave a wide range of small oligopeptides, including neuroactive peptides. We have used force biased molecular dynamics simulation to study the binding mechanism of POP. We examined three possible binding pathways using Steered Molecula...

We investigated the contribution of frontal and parietal cortices to bottom-up and top-down visual attention using electrophysiological measures in humans. Stimuli consisted of triangles, each with a different color and orientation. Subjects were presented with a sample triangle which served as the target for that trial. An array was subsequently presented with the target and three additional d...