A 52-year-old man experienced fever, sore throat, and rhinorrhea for several days. Some days after resolution he developed dizziness, paresthesia on the hands, and unsteady gait. Ocular movement was not limited. His gait was ataxic and no limb weakness on Romberg sign was evident. Muscle stretch reflexes were absent. Acute cerebellar ataxia was suspected. Anti-GQ1b antibody, however, was detect...

We discuss two of the most common of the acquired inflammatory neuropathies: Guillain-Barre syndrome and chronic inflammatory demyelinating polyneuropathy, as well as their variants. We review their clinical presentation, electrophysiologic findings, and management, highlighting knowledge gained from the recent literature. Unfortunately, although treatments exist for both Guillain-Barre syndrom...

We report an unusual case of Guillain-Barre syndrome in a 36-year old gentleman, diagnosed based on clinical presentation, CSF analysis and nerve study tests findings, who presented to our department for elective cystoscopy and discovered at the day of surgery to have macular skin rash over the trunk and upper limbs, surgery was postponed. Then and after 12 hours he started to develop the class...

Miller Fisher syndrome (MFS), a variant of Guillain-Barré syndrome, is a rare disorder typically characterized by a triad of ataxia, areflexia, and ophthalmoplegia, which may have a highly variable clinical presentation. We report a case of MFS in a 45-year-old female presenting with sphenoid sinusitis and sixth nerve palsy. She underwent endoscopic sphenoid sinusotomy without improvement, had ...

An 80-year-old woman presented with simultaneous increasing muscle weakness and nephrotic syndrome. A renal biopsy confirmed focal segmental glomerulosclerosis (FSGS). Her neurological diagnosis best fitted with a Guillain-Barre-like syndrome. There have been several cases of FSGS in combination with both conventional and atypical Guillain-Barre syndrome (GBS). Our patient was treated with high...

introduction guillain-barre syndrome (gbs) is an immune-mediated acute inflammatory disorder of the peripheral nervous system. infectious agents were usually accused of playing a role in the etiology of gbs. guillain-barre syndrome has rarely been reported following subdural and subarachnoid hemorrhage after head trauma. case presentation we report on a 63-year-old male patient presenting gbs f...

how to cite this article: talebian a, soltani b, talebian m. bilateral ptosis as the first presentation of guillain-barre syndrome. iran j child neurol. winter 2016; 10(1):70-72. abstract objective guillain-barre syndrome (gbs) is the most common cause of acute weakness in children. it has multiple variant forms with different presentations. a rare initial sign is ptosis. in this study, we pres...