This cross-sectional study tested the hypothesis that decreased serum levels of tetranectin (TN), a regulator of the fibrinolysis and proteolytic system, is associated with the presence and severity of CAD. We conducted a systematic serological and immunohistochemical (IHC) analysis to respectively compare the TN levels in serum and artery samples in CAD patients and healthy controls. Our resul...

1 Institute for Functional Imaging of Materials, Oak Ridge National Laboratory, Oak Ridge, TN 37831 2 Center for Nanophase Materials Sciences, Oak Ridge National Laboratory, Oak Ridge, TN 37831 3 Materials Science & Technology Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 4 Computer Science and Mathematics Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 5 Computation...

M. E. Loveless, J. Halliday, C. Liess, L. Xu, R. Dortch, J. Whisenant, J. C. Waterton, J. C. Gore, and T. E. Yankeelov Biomedical Engineering, Vanderbilt University, Nashville, TN, United States, Institute of Imaging Science, Vanderbilt University, Nashville, TN, United States, Imaging, Translational Sciences, AstraZeneca, Macclesfield, Cheshire, United Kingdom, Biostatistics, Vanderbilt Univer...

Department of Biological Sciences, Michigan Technological University, Houghton, MI, USA, Department of Civil and Environmental Engineering, University of Tennessee, Knoxville, TN, USA, Center for Environmental Biotechnology, University of Tennessee, Knoxville, TN, USA, 4 Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA, Graduate School of Genome Science and Technology, Un...

PURPOSE To find out an effective prognostic factor for early stage non-small cell lung cancer (NSCLC), we examined the relationship of the degree of tenascin-C (TN-C) degradation in relapsed NSCLC tumors with the prognosis of the patients. The molecular mechanism of TN-C degradation was also evaluated. EXPERIMENTAL DESIGN In 63 stage-1 NSCLC patients, TN-C protein was analyzed by Western blot...

a Psychiatric Neuroimaging Program, Vanderbilt Psychiatric Hospital, Suite 3057, 1601 23rd Ave. S., Nashville, TN 37212, USA b Department of Psychology, Vanderbilt University, Nashville, TN, USA c Vanderbilt Institute of Imaging Sciences, Vanderbilt University, Nashville, TN, USA d Department of Nuclear Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA e Department of Radiolog...

T. K. Sinha, Z. K. Yang, E. H. Seeley, M. Loveless, D. C. Colvin, R. M. Caprioli, and J. C. Gore Radiology and Radiological Sciences, Vanderbilt University, Nashville, TN, United States, Chemical and Physical Biology, Vanderbilt University, Nashville, TN, United States, Mass Spectrometry Research Center, Vanderbilt University, Nashville, TN, United States, Biomedical Engineering, Vanderbilt Uni...

1. Center for Nanophase Materials Sciences, Oak Ridge National Laboratory, Oak Ridge, TN 37831 2. The Institute for Functional Imaging of Materials, Oak Ridge National Laboratory, Oak Ridge, TN 37831 3. Department of Materials Science and Engineering, University of Tennessee, Knoxville, Knoxville TN 37996 4. Materials Sciences and Technology Division, Oak Ridge National Laboratory, Oak Ridge, T...

INTRODUCTION Triple negative (TN) breast cancers are defined by a lack of expression of oestrogen, progesterone, and HER2 receptors. They tend to have a higher grade, with a poorer outcome compared to non-TN breast cancers. OBJECTIVE The aim of this study is to determine the incidence of TN breast cancer in an Asian country consisting of Malays, Chinese and Indians, and to determine the facto...