DRASTIC--Database Resource for the Analysis of Signal Transduction In Cells (http://www.drastic.org.uk/) has been created as a first step towards a data-based approach for constructing signal transduction pathways. DRASTIC is a relational database of plant expressed sequence tags and genes up- or down-regulated in response to various pathogens, chemical exposure or other treatments such as drou...

Dear Editor, A 56-year-old Indian woman with obesity underwent bariatric surgery (laparoscopic sleeve gastrectomy). She had gained 10 kg over the 3 years preceding the surgery after changing to a sedentary job. For 2 years, she had been having localised itch over the paraspinal region of her left upper back. Examination revealed a localised hyperpigmented patch over her left upper back (Fig. 1)...

We have found experimentally that the shot noise of the tunneling current I through an undoped semiconductor superlattice is reduced with respect to the Poissonian noise value 2eI, and that the noise approaches 1/3 of that value in superlattices whose quantum wells are strongly coupled. On the other hand, when the coupling is weak or when a strong electric field is applied to the superlattice, ...

Pectin, an integral component of the plant cell wall, is a recalcitrant substrate against enzymatic challenges by most animals. In characterizing the source of a leaf beetle's (Cassida rubiginosa) pectin-degrading phenotype, we demonstrate its dependency on an extracellular bacterium housed in specialized organs connected to the foregut. Despite possessing the smallest genome (0.27 Mb) of any o...

هدف: هدف پژوهش حاضر تعیین نقش واسطه‌­ای اجتناب تجربی و دشواری‌­های تنظیم هیجان در رابطه بین سازوکارهای دفاعی با افکار خودکشی نوجوانان بود. روش: از نوع توصیفی- همبستگی جامعه آماری این شامل تمام شهر کرج پاییز سال 1398 بود که میان آن­ها به روش نمونه گیری دسترس مناطق آموزشی 3 7، 270 نوجوان 15 تا 18 (125 پسر 143 دختر) انتخاب شدند. ابزار پرسشنامه دفاعی-40 آندروز همکاران (۱۹93) (DSQ-40)؛ دشواری گراتز ...

Modern systems must be adaptable | to changing requirements, bugxes, new technologies and recon guration. For critical applications this must be possible at run-time; for complex applications it should be limitable to major sub-divisions of the system. The DRASTIC architecture addresses these goals by exploiting object persistence and distributed systems implementation techniques. It enables ru...