Introduction It has been said that pigmentation of the skin is the most distinctive feature of Addison's disease (British Medical Journal, 1963) and that no other clinical feature is as useful diagnostically (Dunlop, 1963). Four cases are presented where no pigmentation was found. The difficulties in diagnosis are discussed and it is suggested that Addison's disease without pigmentation is comm...

The severity of inflammation in sympathetic ophthalmia is related to the degree of pigmentation, and the granulomatous response seems to be related to pigmentation. Eosinophilia is also associated with pigmentation, but this association appears to be fortuitous and is a result of the association of eosinophilia with severity of the inflammation.

this study was conducted to examine morphometric and meristic characteristics alongside pigmentation patterns of bream larvae, abramis brama orientalis, in four stages of larval development. morphological characters including total length (tl), standard length (sl), notochord length (nl), head length (hl), head depth (hd), eye diameter (ed) and mouth width (mw) were examined from hatching time ...

Near-infrared fluorescence imaging (NIRFI) and far-red fluorescence imaging (FRFI) were used to investigate effects of depilation-induced skin pigmentation and diet-induced background fluorescence on fluorescent signal amplitude and lymphatic contraction frequency in C57BL6 mice. Far-red fluorescent signal amplitude, but not frequency, was affected by diet-induced fluorescence, which was remove...

Rates of skin cancer continue to increase despite the improved use of traditional sunscreens to minimize damage from ultraviolet radiation. The public perception of tanned skin as being healthy and desirable, combined with the rising demand for treatments to repair irregular skin pigmentation and the desire to increase or decrease constitutive skin pigmentation, arouses great interest pharmaceu...