OBJECTIVE This study evaluated apical transportation associated with ProTaper Universal Fl, F2 and F3 rotary files in curved canais prepared by undergraduate students. MATERIAL AND METHODS Twenty mesial roots of mandibular molars with curvatures ranging between 25° and 35° were selected. Mesiobuccal canals were instrumented by twenty students with the ProTaper system (Dentsply-Maillefer, Ball...

on transcriptional activation by serum response factor. A truncated form of the type II TGF-j3 receptor, created by deletion of the cytoplasmic kinase domain, acts as a dominant suppressor of TGF-f3 signal transduction in cultured cardiac muscle cells and may provide a suitable means to establish the functions of TGF-f3 in vivo. (Circ Res. 1993;73:783-791.)

Let n and r be positive integers. Suppose that a family F ⊂ 2[n] satisfies |F1 ∩ F2 ∩ F3| ≥ 2 for all F1, F2, F3 ∈ F . We prove that if w < 0.5018 then ∑ F∈F w |F |(1− w)n−|F | ≤ w2.

on transcriptional activation by serum response factor. A truncated form of the type II TGF-j3 receptor, created by deletion of the cytoplasmic kinase domain, acts as a dominant suppressor of TGF-f3 signal transduction in cultured cardiac muscle cells and may provide a suitable means to establish the functions of TGF-f3 in vivo. (Circ Res. 1993;73:783-791.)

Dependence of murine pro-B Ba/F3 cells on interleukin-3 can be substituted by GH when cells are stably transfected with the GH receptor (GHR) complementary DNA. Recently, we demonstrated that Ba/F3 cells produce GH, which is responsible for the survival of cells expressing the GHR. This GH effect involves the activation of nuclear factor-kappaB (NF-kappaB). Here, we examined the signaling pathw...

Three major forms of cytosolic glutathione S-transferase (designated F1, F2, and F3 transferases according to increasing isoelectric points) were purified to homogeneity from liver of DBA/2J mice, primarily by CM-cellulose and hydroxylapatite chromatography. The purified enzymes were shown to have specific activities of 104, 281, and 143 units/mg, respectively, when assayed with 1 m~ each of l-...

The objective of this study was to assess the difference in voice quality as defined by acoustical analysis using sustained vowel in laryngectomized patients in comparison with normal volunteers. This was designed as a retrospective single center cohort study. An adult tertiary referral unit formed the setting of this study. Fifty patients (40 males) who underwent total laryngectomy and 31 norm...

Background/Aims Liver stiffness (LS) was assessed using transient elastography, and the enhanced liver fibrosis (ELF) test was performed to accurately assess fibrotic burden. We validated the LS-ELF algorithm and investigated whether the sequential LS-ELF algorithm performs better than concurrent combination of these analyses in chronic hepatitis B (CHB) patients. Methods Between 2009 and 201...

OBJECTIVES To assess and compare the bioavailability of three different oral dosage forms of vitamin A in rats. The formulations included vitamin A self-nanoemulsified drug delivery (SNEDD) optimized formulation-filled capsule (F1), vitamin A SNEDD optimized formulation compressed tablet (F2) and vitamin A oily solution-filled capsules without any additives (control, F3). MATERIALS AND METHOD...

OBJECTIVE Despite modern therapies, pulmonary arterial hypertension (PAH) harbors a high mortality. Vascular remodeling is a hallmark of the disease. Recent clinical studies revealed that antiremodeling approaches with tyrosine-kinase inhibitors such as imatinib are effective, but its applicability is limited by significant side effects. Although imatinib has multiple targets, expression analys...