Core snRNP proteins bind snRNA through the conserved Sm site, PuA(U)n>/=3GPu. While yeast U1 snRNA has three matches to the Sm consensus, the U1 3'-terminal Sm site was found to be both necessary and sufficient for U1 function. Mutation of this site inhibited pre-mRNA splicing, blocked cell division and resulted in the accumulation of two 3'-extended forms of the U1 snRNA. Cells which harbor th...

Measurements of blood–brain barrier permeability in patients undergoing radiotherapy and chemotherapy for primary cerebral lymphoma. Eur J Cancer 1991; 27:1356–61 11. Gray AT, Krejci ST, Larson MD: Neuromuscular blocking drugs do not alter the pupillary light reflex of anesthetized humans. Arch Neurol 1997; 54:579–84 12. Matteo RS, Pua EK, Khambatta HJ, Spector S: Cerebrospinal fluid levels of ...

Diatoms are an important class of unicellular algae that produce bioactive secondary metabolites with cytotoxic activity collectively termed oxylipins, including polyunsaturated aldehydes (PUAs), hydroxyacids (HEPEs), oxo-acids and epoxyalcohols. Previous results showed that at higher concentrations, the PUA decadienal induced apoptosis on copepods and sea urchin embryos via caspase-3 activatio...

OBJECTIVES The purpose of this study was to identify the sources of stress among dental students enrolled at Pharos University in Alexandria (PUA) - Egypt, and to explore the role of gender, level of undergraduate study and residence with parents on perceived stressors. MATERIALS AND METHODS A thirty-item self-reported modified version of the Dental Environment Stress (DES) questionnaire was ...

PVDF and P(VDF-TrFE) nano- and micro- structures have been widely used due to their potential applications in several fields, including sensors, actuators, vital sign transducers, and energy harvesters. In this study, we developed vertically aligned P(VDF-TrFE) core-shell structures using high modulus polyurethane acrylate (PUA) pillars as the support structure to maintain the structural integr...

Every day, thousands of new mobile apps are published on mobile app stores including Google Play and iOS App Store. While many of them are native apps, others are cross-platform mobile apps or HTML-based hybrid apps developed using various cross-platform mobile development tools. Native apps for Android and iOS are usually written using Android SDK and XCode tools respectively, but malware auth...

The goal of the VISION (Video Indexing for SearchIng Over Networks) project is to demonstrate the technology necessary for a comprehensive, on-line digital video library. We have developed automatic mechanisms to populate the library and provide content-based search and retrieval of video over computer networks. The salient feature of our approach is the integrated application of mature image o...