due to the uncensored use of pesticides in the agricultural regions of lebanon, the contaminationrisks of drinking water by organic residues increase periodically in planting seasons. no previous work havebeen considered in north lebanon plain concerning pesticide pollution though it is the second agriculturalzone in lebanon with an excessive activity. in this context, the aim of this study was...

gabapentin is an anticonvulsant widely used in the treatment of epilepsy. no peculiar chromophore is available on the gabapentin moiety for direct analysis by absorption spectrophotometry. a sensitive spectrophotometric method for the determination of gabapentin in bulk, pharmaceutical formulations and human plasma has been developed. in this method, gabapentin directly derivatized with vanilli...

introduction: diazinon is a moderately toxic broad-spectrum organophosphate, with a ld50 of 350 to 400 mg/kg for humans. diazinon is absorbed through the skin and gastrointestinal tract and is rapidly metabolized within a few hours. diazinon residues in melons and cucumbers have recently became a major health concern in iran. thus we decided to investigate diazinon levels in melon and cucumbers...

Objective: Saffron petal is a by-product that contains flavonoids and anthocyanins. In order to study the effects of saffron petal extract (SPE) on blood parameters, immune system, and spleen histology, five treatments (n=6) were used in a completely randomized design. Materials and Methods: The treatments were 0, 75, 150, 225, and 450 mg/kg body weight of SPE. The SPE was injected intraperiton...

Previous studies have identified chemical recovery condensates as a primary source of hormonally active substances within a Canadian bleached kraft pulp mill. Although reverse osmosis treatment of condensates raises the exposure threshold that alters circulating levels of testosterone in mummichog (Fundulus heteroclitus), the responsible chemicals have not been characterized. In this study, a s...

The interaction forces provided by silicone polyether (SPE) surfactants, adsorbed at the interface of octadecyltrichlorosilan monolayer and aqueous surfactant solution, were measured by atomic force microscopy. Changes in the forces in the presence of ethanol were examined for a series of comb-type SPE surfactants. It was found that the steric repulsion provided by the SPE molecules persisted u...

Ornithine decarboxylase (ODC) of the fungus Neurospora crassa, encoded by the spe-1 gene, catalyzes an initial and rate-limiting step in polyamine biosynthesis and is highly regulated by polyamines. In N. crassa, polyamines repress the synthesis and increase the degradation of ODC protein. Changes in the rate of ODC synthesis correlate with similar changes in the abundance of spe-1 mRNA. We ide...

We previously demonstrated that the organic extract of Spirulina platensis (SPE), an edible blue-green alga, possesses potent anti-inflammatory effects. In this study, we investigated if the regulation of histone deacetylases (HDACs) play a role in the anti-inflammatory effect of SPE in macrophages. Treatment of macrophages with SPE rapidly and dose-dependently reduced HDAC2, 3, and 4 proteins ...

Estrone has been identified as a potential endocrine-disrupting chemical (EDC). To facilitate its analysis, a highly selective and sensitive enzyme-linked immunosorbent assay (ELISA) method with a simple solid-phase extraction (SPE) for analysis of estrone in aquatic environments has been developed. The specific polyclonal antibody was produced against a conjugate of estrone-3-hemisuccinate and...