To identify soluble proteins of the retinal interphotoreceptor matrix (IPM), we isolated IPM from the bovine eye by gentle lavage and subjected it to SDS-PAGE. In the resultant gel, a 46 kDa band was particularly prominent and appeared to be a single protein. This protein was electroblotted to nitrocellulose membrane, digested with trypsin, and selected peptides were isolated by HPLC and subjec...

PURPOSE To characterize the genomic organization of human IMPG2, the gene encoding the retinal interphotoreceptor matrix (IPM) proteoglycan IPM 200, to evaluate its relationship to IPM 150, and to evaluate its involvement in inherited retinopathies, such as age-related macular degeneration, retinitis pigmentosa, and Leber congenital amaurosis. METHODS After isolation of human genomic clones, ...

lowing IPM procedures for managing grain aphids. Results Ninety-four percent of the 39 field tests comparing preventive versus IPM practices showed that IPM practices were more profitable. Few fields developed threshold aphid populations so insecticide was not applied and yields were not affected. Money was saved and total pesticide usage was reduced. Surveys of untreated fields over the last t...

OBJECTIVE To explore the usefulness of incidence-prevalence-mortality (IPM) models in improving estimates of disease epidemiology. METHODS Two artificial and four empirical data sets (for breast, prostate, colorectal, and stomach cancer) were employed in IPM models. FINDINGS The internally consistent artificial data sets could be reproduced virtually identically by the models. Our estimates...

Integrated pest management (IPM), which combines physical, biological, and chemical control measures to complementary effect, is one of the most important approaches to environmentally friendly sustainable agriculture. To expand IPM, we need to develop new pest control measures, reinforce existing measures, and investigate interactions between measures. Continued progress in the development of ...

The estimation of dand q-axis parameters is highly desirable, because they are fundamental parameters to many vector control algorithms in the d-q reference frame for fast and accurate responses. Using the finite element method (FEM) for the determination of the interior permanent magnet synchronous motor (IPM) reactance provides an accurate means of determining the field distribution. However,...

This paper deals with analytical methods for calculating the mean age of onset and the mean disease duration in chronic diseases. For this calculation so-called IPM models are used. IPM stands for incidence, prevalence and mortality. First, the general IPM model is introduced. Then, formulas for the mean duration and the mean age of onset of the disease will be developed and applied to epidemio...

As the Internet of Things (IoT) is emerging as an attractive paradigm, a typical IoT architecture that U2IoT (Unit IoT and Ubiquitous IoT) model has been presented for the future IoT. Based on the U2IoT model, this paper proposes a cyber-physical-social based security architecture (IPM) to deal with Information, Physical, and Management security perspectives, and presents how the architectural ...

Rachel Carson's 1962 Silent Spring exposed both observed and potential environmental and health externalities of the increasing organochlorine and organophosphate insecticide use in the United States post-World War II. Silent Spring was a critical component in a popular movement that resulted in increased regulation and the development of safer pesticides. Most changes in pesticide use in the g...

Previous investigations established that focal subretinal injections of neuraminidase, chondroitinase, and hyaluronidase in the rabbit lead to a diffuse loss of retinal adhesiveness beyond the site of injection. This loss of adhesiveness, measured by peeling of the retina immediately after enucleation, correlates with changes in the interphotoreceptor matrix (IPM), as monitored by lectin histoc...