Primary central nervous system lymphoma (PCNSL) is a rare form of non-Hodgkin lymphoma with poor long-term survival. This study assessed methotrexate (MTX) plus idarubicin (IDA) in treating patients of PCNSL comparing to MTX alone therapy. A total of 100 patients were retrospectively enrolled and subjected to MTX alone (n = 52) and MTX plus IDA (n = 48). The completed response (CR) rate in pati...

In order to detect intrusions, IDA (Intrusion Detection Agent system) initially monitors system logs in order to discover an MLSI { which is an certain event which in many cases occurs during an intrusion. If an MLSI is found, then IDA judges whether the MLSI is accompanied by an intrusion. We adopt discriminant analysis to analyze information after IDA detects an MLSI in a remote attack. Discr...

BACKGROUND AND OBJECTIVE Idarubicin (IDA) is relatively immune to the multidrug resistance P-gp mechanism that is frequently expressed in recurrent and refractory hematologic malignancies. Owing to rapid metabolism in vivo, a continuous infusion (CI) of IDA might prolong exposure time to the parent drug rather than its more P-gp susceptible alcohol metabolite. For this reason we developed a bri...

We describe the application of a stable isotope dilution assay (IDA) to determine precise insulin, C-peptide, and proinsulin levels in blood by extraction from serum and quantitation by mass spectrometry using analogues of each target protein labeled with stable isotopes. Insulin and C-peptide levels were also determined by immunoassay, which gave consistently higher results than by IDA, the re...

OBJECTIVES The aim of this study was to examine the relationships between psychological and social factors and late pregnancy IDA among pregnant women in rural Viet Nam. METHODS Pregnant women from 50 randomly-selected communes within Ha Nam province were recruited and assessed at 12 - 20 weeks gestation (Wave 1, W1). They were followed up in the last trimester (Wave 2, W2). IDA was defined a...

RATIONALE The relationship between clinical phenotype of childhood primary ciliary dyskinesia (PCD) and ultrastructural defects and genotype is poorly defined. OBJECTIVES To delineate clinical features of childhood PCD and their associations with ultrastructural defects and genotype. METHODS A total of 118 participants younger than 19 years old with PCD were evaluated prospectively at six c...

Iron deficiency anemia (IDA) is a common nutritional deficiency syndrome. Lead and cadmium are major hazard elements to humans in industrialized countries. Zinc and copper are essential and play important roles in different physiologic and pathologic conditions. The aim of our study was to determine levels of serum Cu, Zn, Fe, Cd and Pb in IDA patients, and to investigate the relationship betwe...

Iron deficiency anemia (IDA) is a frequent disorder. Also, it may be a sign of underlying serious diseases. Iron deficiency points to an occult or frank bleeding lesion when occurred in men or postmenopausal women. In this study, we aimed to evaluate the diagnostic yield of endoscopy in patients with IDA and to define predictive factors of gastrointestinal (GI) lesions causing IDA. Ninety-one p...

this study was conducted to evaluate the association between h. pylori infection and iron deficiency anemia (ida) among preschool children (age range: 40-75 months) at a tertiary referral hospital in tehran.in a case-control study, the prevalence of h. pylori seropositivity was compared between 64 children with ida diagnosis and 70 healthy non-anemic sex- and age-matched controls. totally, 52 (...