This study examines the role played by cyclooxygenase (COX) isoforms (COX-1 and -2) in the regulation of colonic neuromuscular function in normal rats and after induction of colitis by 2,4-dinitrobenzenesulfonic acid (DNBS). The expression of COX-1 and COX-2 in the colonic neuromuscular layer was assessed by reverse transcription-polymerase chain reaction and immunohistochemistry. The effects o...

Endogenous prostaglandins (PGs) are involved in adaptive gastric protection against acute injury, and cyclooxygenase (COX)-1 is responsible for the production of PGs in this phenomenon. In the present study, we examined the effect of various COX inhibitors on gastric ulcerogenic and acid secretory responses following daily exposure of the stomach to iodoacetamide (IA) and investigated the role ...

Prostaglandin formation is enhanced in vascular disease, in part through induction of cyclooxygenase (COX-2) in vascular smooth muscle cells. Because COX regulates cell growth and migration, we examined whether the COX expression plays a role in the development of intimal hyperplasia after vascular injury. Rats undergoing balloon angioplasty of the carotid artery were randomized to receive a se...

Aims. We report the detection of X-ray emission from the jet-driving symbiotic star MWC 560. Methods. We observed MWC 560 with XMM-Newton for 36 ks. We fitted the spectra from the EPIC pn, MOS1 and MOS2 instruments with XSPEC and examined the light curves with the package XRONOS. Results. The spectrum can be fitted with a highly absorbed hard X-ray component from an optically-thin hot plasma, a...

In this paper, an RTAI-Linux based distributed platform for the control of the PUMA 560 robotic manipulator is presented. From the mechanical point of view, the PUMA 560, besides being one of the first and most popular 6-DOF anthropomorphic manipulator, is still a very good example of implementation of small size robotic arms. On the other hand, its original control system, if compared to moder...