Birdsey, T. J., R. D. H. Boyd, C. P. Sibley, and S. L. Greenwood. Effect of hyposmotic challenge on microvillous membrane potential in isolated human placental villi. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R1479–R1488, 1999.—This study examined the effect of hyposmotic solutions on the syncytiotrophoblast microvillous membrane potential (Em) in mature intermediate villi...

Feldenberg, L. Richard, Sundararajah Thevananther, Marcela Del Rio, Maryely De Leon, and Prasad Devarajan. Partial ATP depletion induces Fasand caspasemediated apoptosis in MDCK cells. Am. J. Physiol. 276 (Renal Physiol. 45): F837–F846, 1999.—Brief periods of in vitro hypoxia/ischemia induce apoptosis of cultured renal epithelial cells, but the underlying mechanisms remain unknown. We show that...

Masada, Kimiya, Takahiro Nagayama, Akio Hosokawa, Makoto Yoshida, Mizue Suzuki-Kusaba, Hiroaki Hisa, Tomohiko Kimura, and Susumu Satoh. Effects of adrenomedullin and PAMP on adrenal catecholamine release in dogs. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R1118–R1124, 1999.—We examined the effects of proadrenomedullin-derived peptides on the release of adrenal catecholamine...

Landesberg, Amir, and Samuel Sideman. Regulation of energy consumption in cardiac muscle: analysis of isometric contractions. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H998–H1011, 1999.—The well-known linear relationship between oxygen consumption and force-length area or the force-time integral is analyzed here for isometric contractions. The analysis, which is based on a biochemical mode...

Weiner, I. David, Amy E. Frank, and Charles S. Wingo. Apical proton secretion by the inner stripe of the outer medullary collecting duct. Am. J. Physiol. 276 (Renal Physiol. 45): F606–F613, 1999.—The inner stripe of outer medullary collecting duct (OMCDis) is unique among collecting duct segments because both intercalated cells and principal cells secrete protons and reabsorb luminal bicarbonat...

Alexander, EdwardA., Dennis Brown, Theodora Shih, Mary McKee, and John H. Schwartz. Effect of acidification on the location of H1-ATPase in cultured inner medullary collecting duct cells. Am. J. Physiol. 276 (Cell Physiol. 45): C758–C763, 1999.—In previous studies, our laboratory has utilized a cell line derived from the rat inner medullary collecting duct (IMCD) as a model system for mammalian...

Jensen, Michael E., and Edward J. Messina. C-peptide induces a concentration-dependent dilation of skeletal muscle arterioles only in presence of insulin. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H1223–H1228, 1999.—In this study we tested the hypothesis that C-peptide alone or in conjunction with insulin may cause a dilation of skeletal muscle arterioles. First-order arterioles (88 μm) is...

Art in particular painting, has had clear impacts on the style, techniques, and processes of scientific visualization. Artists strive to create visual forms and ideas that are evocative and convey meaning or tell a story. Over time, painters and other artists have developed sophisticated techniques, as well as a finely tuned aesthetic sense, to help accomplish their goals. As visual-ization res...

Schlüter, Klaus-Dieter, Andreas Simm, Matthias Schäfer, Gerhild Taimor, and Hans Michael Piper. Early response kinase and PI 3-kinase activation in adult cardiomyocytes and their role in hypertrophy. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H1655–H1663, 1999.—The present study investigated the role of early response kinase (ERK) and phosphatidylinositol 3 (PI 3)-kinase in ventricular card...

Seo, J. T., H. Sugiya, S. I. Lee, M. C. Steward, and A. C. Elliott. Caffeine does not inhibit substance P-evoked intracellular Ca21 mobilization in rat salivary acinar cells. Am. J. Physiol. 276 (Cell Physiol. 45): C915–C922, 1999.—We used the Ca21-sensitive fluorescent dye fura 2, together with measurements of intracellular D-myo-inositol 1,4,5-trisphosphate [Ins(1,4,5)P3], to assess the inhib...